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Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010.

Publication ,  Journal Article
Zhang, AS; Ostrom, QT; Kruchko, C; Rogers, L; Peereboom, DM; Barnholtz-Sloan, JS
Published in: Neuro Oncol
May 1, 2017

BACKGROUND: Complete prevalence proportions illustrate the burden of disease in a population. This study estimates the 2010 complete prevalence of malignant primary brain tumors overall and by Central Brain Tumor Registry of the United States (CBTRUS) histology groups, and compares the brain tumor prevalence estimates to the complete prevalence of other common cancers as determined by the Surveillance, Epidemiology, and End Results Program (SEER) by age at prevalence (2010): children (0-14 y), adolescent and young adult (AYA) (15-39 y), and adult (40+ y). METHODS: Complete prevalence proportions were estimated using a novel regression method extended from the Completeness Index Method, which combines survival and incidence data from multiple sources. In this study, two datasets, CBTRUS and SEER, were used to calculate complete prevalence estimates of interest. RESULTS: Complete prevalence for malignant primary brain tumors was 47.59/100000 population (22.31, 48.49, and 57.75/100000 for child, AYA, and adult populations). The most prevalent cancers by age were childhood leukemia (36.65/100000), AYA melanoma of the skin (66.21/100000), and adult female breast (1949.00/100000). The most prevalent CBTRUS histologies in children and AYA were pilocytic astrocytoma (6.82/100000, 5.92/100000), and glioblastoma (12.76/100000) in adults. CONCLUSIONS: The relative impact of malignant primary brain tumors is higher among children than any other age group; it emerges as the second most prevalent cancer among children. Complete prevalence estimates for primary malignant brain tumors fills a gap in overall cancer knowledge, which provides critical information toward public health and health care planning, including treatment, decision making, funding, and advocacy programs.

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Published In

Neuro Oncol

DOI

EISSN

1523-5866

Publication Date

May 1, 2017

Volume

19

Issue

5

Start / End Page

726 / 735

Location

England

Related Subject Headings

  • Young Adult
  • United States
  • Survival Rate
  • SEER Program
  • Registries
  • Prognosis
  • Prevalence
  • Oncology & Carcinogenesis
  • Neoplasms
  • Middle Aged
 

Citation

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ICMJE
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Zhang, A. S., Ostrom, Q. T., Kruchko, C., Rogers, L., Peereboom, D. M., & Barnholtz-Sloan, J. S. (2017). Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010. Neuro Oncol, 19(5), 726–735. https://doi.org/10.1093/neuonc/now252
Zhang, Adah S., Quinn T. Ostrom, Carol Kruchko, Lisa Rogers, David M. Peereboom, and Jill S. Barnholtz-Sloan. “Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010.Neuro Oncol 19, no. 5 (May 1, 2017): 726–35. https://doi.org/10.1093/neuonc/now252.
Zhang AS, Ostrom QT, Kruchko C, Rogers L, Peereboom DM, Barnholtz-Sloan JS. Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010. Neuro Oncol. 2017 May 1;19(5):726–35.
Zhang, Adah S., et al. “Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010.Neuro Oncol, vol. 19, no. 5, May 2017, pp. 726–35. Pubmed, doi:10.1093/neuonc/now252.
Zhang AS, Ostrom QT, Kruchko C, Rogers L, Peereboom DM, Barnholtz-Sloan JS. Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010. Neuro Oncol. 2017 May 1;19(5):726–735.
Journal cover image

Published In

Neuro Oncol

DOI

EISSN

1523-5866

Publication Date

May 1, 2017

Volume

19

Issue

5

Start / End Page

726 / 735

Location

England

Related Subject Headings

  • Young Adult
  • United States
  • Survival Rate
  • SEER Program
  • Registries
  • Prognosis
  • Prevalence
  • Oncology & Carcinogenesis
  • Neoplasms
  • Middle Aged