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An updated histology recode for the analysis of primary malignant and nonmalignant brain and other central nervous system tumors in the Surveillance, Epidemiology, and End Results Program.

Publication ,  Journal Article
Forjaz, G; Barnholtz-Sloan, JS; Kruchko, C; Siegel, R; Negoita, S; Ostrom, QT; Dickie, L; Ruhl, J; Van Dyke, A; Patil, N; Cioffi, G; Waite, K ...
Published in: Neurooncol Adv
2021

BACKGROUND: There are over 100 histologically distinct types of primary malignant and nonmalignant brain and other central nervous system (CNS) tumors. Our study presents recent trends in the incidence of these tumors using an updated histology recode that incorporates major diagnostic categories listed in the 2016 World Health Organization Classification of Tumours of the CNS. METHODS: We used data from the SEER-21 registries for patients of all ages diagnosed in 2000-2017. We calculated age-adjusted incidence rates and fitted a joinpoint regression to the observed data to estimate the Annual Percent Change and 95% confidence intervals over the period 2000-2017. RESULTS: There were 315,184 new malignant (34.2%; 107,890) and nonmalignant (65.8%; 207,294) brain tumor cases during 2004-2017. Nonmalignant meningioma represented 46.5% (146,498) of all brain tumors (malignant and nonmalignant), while glioblastoma represented 50.8% (54,832) of all malignant tumors. Temporal trends were stable or declining except for nonmalignant meningioma (0.7% per year during 2004-2017). Several subtypes presented decreases in trends in the most recent period (2013-2017): diffuse/anaplastic astrocytoma (-1.3% per year, oligodendroglioma (-2.6%), pilocytic astrocytoma (-3.8%), and malignant meningioma (-5.9%). CONCLUSIONS: Declining trends observed in our study may be attributable to recent changes in diagnostic classification and the coding practices stemming from those changes. The recode used in this study enables histology reporting to reflect the changes. It also provides a first step toward the reporting of malignant and nonmalignant brain and other CNS tumors in the Surveillance, Epidemiology, and End Results (SEER) Program by clinically relevant histology groupings.

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Published In

Neurooncol Adv

DOI

EISSN

2632-2498

Publication Date

2021

Volume

3

Issue

1

Start / End Page

vdaa175

Location

England
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Forjaz, G., Barnholtz-Sloan, J. S., Kruchko, C., Siegel, R., Negoita, S., Ostrom, Q. T., … Mariotto, A. B. (2021). An updated histology recode for the analysis of primary malignant and nonmalignant brain and other central nervous system tumors in the Surveillance, Epidemiology, and End Results Program. Neurooncol Adv, 3(1), vdaa175. https://doi.org/10.1093/noajnl/vdaa175
Forjaz, Gonçalo, Jill S. Barnholtz-Sloan, Carol Kruchko, Rebecca Siegel, Serban Negoita, Quinn T. Ostrom, Lois Dickie, et al. “An updated histology recode for the analysis of primary malignant and nonmalignant brain and other central nervous system tumors in the Surveillance, Epidemiology, and End Results Program.Neurooncol Adv 3, no. 1 (2021): vdaa175. https://doi.org/10.1093/noajnl/vdaa175.
Forjaz G, Barnholtz-Sloan JS, Kruchko C, Siegel R, Negoita S, Ostrom QT, Dickie L, Ruhl J, Van Dyke A, Patil N, Cioffi G, Miller KD, Waite K, Mariotto AB. An updated histology recode for the analysis of primary malignant and nonmalignant brain and other central nervous system tumors in the Surveillance, Epidemiology, and End Results Program. Neurooncol Adv. 2021;3(1):vdaa175.

Published In

Neurooncol Adv

DOI

EISSN

2632-2498

Publication Date

2021

Volume

3

Issue

1

Start / End Page

vdaa175

Location

England