Quantitative Methods for HIV/AIDS Research
Quantitative methods and bayesian models for flow cytometry analysis in HIV/AIDS research
Publication
, Chapter
Lin, L; Chan, C
January 1, 2017
Flow cytometry is a multiparameter single-cell assay ubiquitous in HIV/AIDS clinical and research settings for evaluating the immune response to the virus, therapy, and vaccination. In clinical practice, flow cytometry is used to monitor the CD4 and CD8 T cell counts of HIV-infected subjects. In research settings, flow cytometry is used to evaluate innate and antigen-specific responses to the HIV virus, so as to better understand pathogenesis, the mechanisms responsible for long-term nonprogression, and to develop effective immune-based interventions. In vaccine development, there is significant interest in the potential of flow-based biomarkers that can serve as surrogate measures of efficacy.
Duke Scholars
DOI
ISBN
9781498734233
Publication Date
January 1, 2017
Start / End Page
135 / 156
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Lin, L., & Chan, C. (2017). Quantitative methods and bayesian models for flow cytometry analysis in HIV/AIDS research. In Quantitative Methods for HIV/AIDS Research (pp. 135–156). https://doi.org/10.1201/9781315120805
Lin, L., and C. Chan. “Quantitative methods and bayesian models for flow cytometry analysis in HIV/AIDS research.” In Quantitative Methods for HIV/AIDS Research, 135–56, 2017. https://doi.org/10.1201/9781315120805.
Lin L, Chan C. Quantitative methods and bayesian models for flow cytometry analysis in HIV/AIDS research. In: Quantitative Methods for HIV/AIDS Research. 2017. p. 135–56.
Lin, L., and C. Chan. “Quantitative methods and bayesian models for flow cytometry analysis in HIV/AIDS research.” Quantitative Methods for HIV/AIDS Research, 2017, pp. 135–56. Scopus, doi:10.1201/9781315120805.
Lin L, Chan C. Quantitative methods and bayesian models for flow cytometry analysis in HIV/AIDS research. Quantitative Methods for HIV/AIDS Research. 2017. p. 135–156.
DOI
ISBN
9781498734233
Publication Date
January 1, 2017
Start / End Page
135 / 156