Skip to main content
Journal cover image

A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility.

Publication ,  Journal Article
Rinaldi, MA; Liu, J; Enders, TA; Bartel, B; Strader, LC
Published in: Plant molecular biology
July 2012

Auxin regulates many aspects of plant development, in part, through degradation of the Aux/IAA family of transcriptional repressors. Consequently, stabilizing mutations in several Aux/IAA proteins confer reduced auxin responsiveness. However, of the 29 apparent Aux/IAA proteins in Arabidopsis thaliana, fewer than half have roles established through mutant analysis. We identified iaa16-1, a dominant gain-of-function mutation in IAA16 (At3g04730), in a novel screen for reduced root responsiveness to abscisic acid. The iaa16-1 mutation also confers dramatically reduced auxin responses in a variety of assays, markedly restricts growth of adult plants, and abolishes fertility when homozygous. We compared iaa16-1 phenotypes with those of dominant mutants defective in the closely related IAA7/AXR2, IAA14/SLR, and IAA17/AXR3, along with the more distantly related IAA28, and found overlapping but distinct patterns of developmental defects. The identification and characterization of iaa16-1 provides a fuller understanding of the IAA7/IAA14/IAA16/IAA17 clade of Aux/IAA proteins and the diverse roles of these repressors in hormone response and plant development.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Plant molecular biology

DOI

EISSN

1573-5028

ISSN

0167-4412

Publication Date

July 2012

Volume

79

Issue

4-5

Start / End Page

359 / 373

Related Subject Headings

  • Signal Transduction
  • Sequence Homology, Amino Acid
  • Plant Roots
  • Plant Growth Regulators
  • Plant Biology & Botany
  • Phylogeny
  • Phenotype
  • Mutation
  • Multigene Family
  • Molecular Sequence Data
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Rinaldi, M. A., Liu, J., Enders, T. A., Bartel, B., & Strader, L. C. (2012). A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility. Plant Molecular Biology, 79(4–5), 359–373. https://doi.org/10.1007/s11103-012-9917-y
Rinaldi, Mauro A., James Liu, Tara A. Enders, Bonnie Bartel, and Lucia C. Strader. “A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility.Plant Molecular Biology 79, no. 4–5 (July 2012): 359–73. https://doi.org/10.1007/s11103-012-9917-y.
Rinaldi MA, Liu J, Enders TA, Bartel B, Strader LC. A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility. Plant molecular biology. 2012 Jul;79(4–5):359–73.
Rinaldi, Mauro A., et al. “A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility.Plant Molecular Biology, vol. 79, no. 4–5, July 2012, pp. 359–73. Epmc, doi:10.1007/s11103-012-9917-y.
Rinaldi MA, Liu J, Enders TA, Bartel B, Strader LC. A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility. Plant molecular biology. 2012 Jul;79(4–5):359–373.
Journal cover image

Published In

Plant molecular biology

DOI

EISSN

1573-5028

ISSN

0167-4412

Publication Date

July 2012

Volume

79

Issue

4-5

Start / End Page

359 / 373

Related Subject Headings

  • Signal Transduction
  • Sequence Homology, Amino Acid
  • Plant Roots
  • Plant Growth Regulators
  • Plant Biology & Botany
  • Phylogeny
  • Phenotype
  • Mutation
  • Multigene Family
  • Molecular Sequence Data