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Biological Aspects of Cancer Health Disparities.

Publication ,  Book
Freedman, JA; Al Abo, M; Allen, TA; Piwarski, SA; Wegermann, K; Patierno, SR
January 27, 2021

Racial and ethnic disparities span the continuum of cancer care and are driven by a complex interplay among social, psychosocial, lifestyle, environmental, health system, and biological determinants of health. Research is needed to identify these determinants of cancer health disparities and to develop interventions to achieve cancer health equity. Herein, we focus on the overall burden of ancestry-related molecular alterations, the functional significance of the alterations in hallmarks of cancer, and the implications of the alterations for precision oncology and immuno-oncology. In conclusion, we reflect on the importance of estimating ancestry, improving diverse racial and ethnic participation in cancer clinical trials, and examining the intersection among determinants of cancer health disparities.

Duke Scholars

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DOI

Publication Date

January 27, 2021

Volume

72

Start / End Page

229 / 241

Related Subject Headings

  • Neoplasms
  • Humans
  • Healthcare Disparities
  • Health Services Accessibility
  • Global Health
  • General & Internal Medicine
  • Ethnicity
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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Freedman, J. A., Al Abo, M., Allen, T. A., Piwarski, S. A., Wegermann, K., & Patierno, S. R. (2021). Biological Aspects of Cancer Health Disparities. (Vol. 72, pp. 229–241). https://doi.org/10.1146/annurev-med-070119-120305
Freedman, Jennifer A., Muthana Al Abo, Tyler A. Allen, Sean A. Piwarski, Kara Wegermann, and Steven R. Patierno. Biological Aspects of Cancer Health Disparities. Vol. 72, 2021. https://doi.org/10.1146/annurev-med-070119-120305.
Freedman JA, Al Abo M, Allen TA, Piwarski SA, Wegermann K, Patierno SR. Biological Aspects of Cancer Health Disparities. Vol. 72. 2021.
Freedman, Jennifer A., et al. Biological Aspects of Cancer Health Disparities. Vol. 72, 2021, pp. 229–41. Pubmed, doi:10.1146/annurev-med-070119-120305.
Freedman JA, Al Abo M, Allen TA, Piwarski SA, Wegermann K, Patierno SR. Biological Aspects of Cancer Health Disparities. 2021. p. 229–241.

DOI

Publication Date

January 27, 2021

Volume

72

Start / End Page

229 / 241

Related Subject Headings

  • Neoplasms
  • Humans
  • Healthcare Disparities
  • Health Services Accessibility
  • Global Health
  • General & Internal Medicine
  • Ethnicity
  • 3202 Clinical sciences
  • 1103 Clinical Sciences