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Impact of treatment improvement on long-term anxiety: Results from CAMS and CAMELS.

Publication ,  Journal Article
Crane, ME; Norris, LA; Frank, HE; Klugman, J; Ginsburg, GS; Keeton, C; Albano, AM; Piacentini, J; Peris, TS; Compton, SN; Sakolsky, D ...
Published in: J Consult Clin Psychol
February 2021

OBJECTIVE: This article examined associations between change in youth and family characteristics during youth anxiety treatment and long-term anxiety severity and overall functioning. METHOD: Participants (N = 488; age 7-17 years; 45% male; 82% white) were randomized to 12 weeks of cognitive behavioral therapy (Coping Cat), medication (sertraline), their combination, or pill placebo in the Child/Adolescent Anxiety Multimodal Study (CAMS). A subset participated in the naturalistic follow-up Child/Adolescent Anxiety Multimodal Extended Long-term Study (CAMELS; n = 319; 3.70-11.83 years post-treatment). The current secondary analyses examined how change in anxiety severity (Child Global Impression-Severity), overall functioning (Children's Global Assessment Scale), caregiver psychopathology (Brief Symptom Inventory), caregiver strain (Family Burden Assessment Scale), and family dysfunction (Brief Family Assessment Measure) during CAMS was associated with anxiety severity and overall functioning years later (M = 7.72 years). CAMS procedures were registered on clinialtrials.gov. RESULTS: Improvements in factors related to functioning (i.e., overall functioning, family dysfunction, caregiver strain) were associated with improvements in anxiety severity in CAMELS (|βys| ≥ .04, ps ≤ .04). Improvements in factors related to psychopathology (i.e., anxiety severity, caregiver psychopathology) were associated with improvements in overall functioning in CAMELS (|βys| ≥ .23, ps ≤ .04). It was changes in each of the variables examined (rather than baseline values) that predicted anxiety severity and overall functioning. CONCLUSIONS: Both youth and family factors play a significant role in long-term treatment outcomes. Therapists would be wise to monitor how these factors change throughout treatment. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

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Published In

J Consult Clin Psychol

DOI

EISSN

1939-2117

Publication Date

February 2021

Volume

89

Issue

2

Start / End Page

126 / 133

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Sertraline
  • Selective Serotonin Reuptake Inhibitors
  • Male
  • Longitudinal Studies
  • Humans
  • Female
  • Combined Modality Therapy
  • Cognitive Behavioral Therapy
  • Clinical Psychology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Crane, M. E., Norris, L. A., Frank, H. E., Klugman, J., Ginsburg, G. S., Keeton, C., … Kendall, P. C. (2021). Impact of treatment improvement on long-term anxiety: Results from CAMS and CAMELS. J Consult Clin Psychol, 89(2), 126–133. https://doi.org/10.1037/ccp0000523
Crane, Margaret E., Lesley A. Norris, Hannah E. Frank, Joshua Klugman, Golda S. Ginsburg, Courtney Keeton, Anne Marie Albano, et al. “Impact of treatment improvement on long-term anxiety: Results from CAMS and CAMELS.J Consult Clin Psychol 89, no. 2 (February 2021): 126–33. https://doi.org/10.1037/ccp0000523.
Crane ME, Norris LA, Frank HE, Klugman J, Ginsburg GS, Keeton C, et al. Impact of treatment improvement on long-term anxiety: Results from CAMS and CAMELS. J Consult Clin Psychol. 2021 Feb;89(2):126–33.
Crane, Margaret E., et al. “Impact of treatment improvement on long-term anxiety: Results from CAMS and CAMELS.J Consult Clin Psychol, vol. 89, no. 2, Feb. 2021, pp. 126–33. Pubmed, doi:10.1037/ccp0000523.
Crane ME, Norris LA, Frank HE, Klugman J, Ginsburg GS, Keeton C, Albano AM, Piacentini J, Peris TS, Compton SN, Sakolsky D, Birmaher B, Kendall PC. Impact of treatment improvement on long-term anxiety: Results from CAMS and CAMELS. J Consult Clin Psychol. 2021 Feb;89(2):126–133.

Published In

J Consult Clin Psychol

DOI

EISSN

1939-2117

Publication Date

February 2021

Volume

89

Issue

2

Start / End Page

126 / 133

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Sertraline
  • Selective Serotonin Reuptake Inhibitors
  • Male
  • Longitudinal Studies
  • Humans
  • Female
  • Combined Modality Therapy
  • Cognitive Behavioral Therapy
  • Clinical Psychology