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Cutaneous involvement by T-cell prolymphocytic leukemia presenting as livedoid vasculopathy.

Publication ,  Journal Article
Leckey, BD; Kheterpal, MK; Selim, MA; Al-Rohil, RN
Published in: J Cutan Pathol
July 2021

T-cell prolymphocytic leukemia (T-PLL) is a rare, aggressive neoplasm derived from post-thymic T-cells. Patients are typically middle aged with a slight male predominance who present with a high white blood cell count, hepatosplenomegaly, lymphadenopathy, and other symptoms typically associated with leukemia. Although cutaneous involvement has been reported in up to 30% of cases of T-PLL, to our knowledge, none have presented with a presentation resembling livedoid vasculopathy. In the correct clinical context, an underlying hematolymphoid neoplasm should be included in the differential diagnosis of a patient presenting with livedoid vasculopathy.

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Published In

J Cutan Pathol

DOI

EISSN

1600-0560

Publication Date

July 2021

Volume

48

Issue

7

Start / End Page

975 / 979

Location

United States

Related Subject Headings

  • Vascular Diseases
  • Torso
  • Skin Neoplasms
  • Male
  • Leukemia, Prolymphocytic, T-Cell
  • Immunohistochemistry
  • Hyperpigmentation
  • Humans
  • Fatal Outcome
  • Extremities
 

Citation

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Leckey, B. D., Kheterpal, M. K., Selim, M. A., & Al-Rohil, R. N. (2021). Cutaneous involvement by T-cell prolymphocytic leukemia presenting as livedoid vasculopathy. J Cutan Pathol, 48(7), 975–979. https://doi.org/10.1111/cup.14023
Leckey, Bruce D., Meenal K. Kheterpal, M Angelica Selim, and Rami N. Al-Rohil. “Cutaneous involvement by T-cell prolymphocytic leukemia presenting as livedoid vasculopathy.J Cutan Pathol 48, no. 7 (July 2021): 975–79. https://doi.org/10.1111/cup.14023.
Leckey BD, Kheterpal MK, Selim MA, Al-Rohil RN. Cutaneous involvement by T-cell prolymphocytic leukemia presenting as livedoid vasculopathy. J Cutan Pathol. 2021 Jul;48(7):975–9.
Leckey, Bruce D., et al. “Cutaneous involvement by T-cell prolymphocytic leukemia presenting as livedoid vasculopathy.J Cutan Pathol, vol. 48, no. 7, July 2021, pp. 975–79. Pubmed, doi:10.1111/cup.14023.
Leckey BD, Kheterpal MK, Selim MA, Al-Rohil RN. Cutaneous involvement by T-cell prolymphocytic leukemia presenting as livedoid vasculopathy. J Cutan Pathol. 2021 Jul;48(7):975–979.
Journal cover image

Published In

J Cutan Pathol

DOI

EISSN

1600-0560

Publication Date

July 2021

Volume

48

Issue

7

Start / End Page

975 / 979

Location

United States

Related Subject Headings

  • Vascular Diseases
  • Torso
  • Skin Neoplasms
  • Male
  • Leukemia, Prolymphocytic, T-Cell
  • Immunohistochemistry
  • Hyperpigmentation
  • Humans
  • Fatal Outcome
  • Extremities