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Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives.

Publication ,  Journal Article
Wong, ZS; Borrelli, SLS; Coyne, CC; Boyle, JP
Published in: Int J Parasitol
May 2020

Toxoplasma gondii is remarkably unique in its ability to successfully infect vertebrate hosts from multiple phyla and can successfully infect most cells within these organisms. The infection outcome in each of these species is determined by the complex interaction between parasite and host genotype. As techniques to quantify global changes in cell function become more readily available and precise, new data are coming to light about how (i) different host cell types respond to parasitic infection and (ii) different parasite species impact the host. Here we focus on recent studies comparing the response to intracellular parasitism by different cell types and insights into understanding host-parasite interactions from comparative studies on T. gondii and its close extant relatives.

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Published In

Int J Parasitol

DOI

EISSN

1879-0135

Publication Date

May 2020

Volume

50

Issue

5

Start / End Page

423 / 431

Location

England

Related Subject Headings

  • Virulence
  • Tumor Suppressor Protein p53
  • Transcriptome
  • Toxoplasmosis
  • Toxoplasma
  • THP-1 Cells
  • Protozoan Proteins
  • Protein Serine-Threonine Kinases
  • Neospora
  • Mycology & Parasitology
 

Citation

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Wong, Z. S., Borrelli, S. L. S., Coyne, C. C., & Boyle, J. P. (2020). Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives. Int J Parasitol, 50(5), 423–431. https://doi.org/10.1016/j.ijpara.2020.05.001
Wong, Zhee S., Sarah L Sokol Borrelli, Carolyn C. Coyne, and Jon P. Boyle. “Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives.Int J Parasitol 50, no. 5 (May 2020): 423–31. https://doi.org/10.1016/j.ijpara.2020.05.001.
Wong ZS, Borrelli SLS, Coyne CC, Boyle JP. Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives. Int J Parasitol. 2020 May;50(5):423–31.
Wong, Zhee S., et al. “Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives.Int J Parasitol, vol. 50, no. 5, May 2020, pp. 423–31. Pubmed, doi:10.1016/j.ijpara.2020.05.001.
Wong ZS, Borrelli SLS, Coyne CC, Boyle JP. Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives. Int J Parasitol. 2020 May;50(5):423–431.
Journal cover image

Published In

Int J Parasitol

DOI

EISSN

1879-0135

Publication Date

May 2020

Volume

50

Issue

5

Start / End Page

423 / 431

Location

England

Related Subject Headings

  • Virulence
  • Tumor Suppressor Protein p53
  • Transcriptome
  • Toxoplasmosis
  • Toxoplasma
  • THP-1 Cells
  • Protozoan Proteins
  • Protein Serine-Threonine Kinases
  • Neospora
  • Mycology & Parasitology