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Utility of patient-reported outcomes measurement information system (PROMIS) physical function form in inflammatory myopathy.

Publication ,  Journal Article
Saygin, D; Oddis, CV; Dzanko, S; Koontz, D; Moghadam-Kia, S; Ardalan, K; Coles, TM; Aggarwal, R
Published in: Semin Arthritis Rheum
June 2021

OBJECTIVE: Idiopathic inflammatory myopathies (IIM) are a group of diseases characterized by muscle weakness, which limit activities of daily living. Patient Reported Outcomes Measurement Information System (PROMIS) is a set of outcome measures developed using NIH funding, but has not yet been studied in adult IIM. Currently, the most commonly used PROs in IIM are Health Assessment Questionnaire (HAQ-DI) and SF-36 physical function-10 (PF10), both of which have several limitations. In this study, we investigated psychometric properties of PROMIS physical function-20 (PF-20) and compared to HAQ-DI and SF-36 PF10. METHODS: Patients with IIM completed PROMIS PF-20 and six myositis core set measures [manual muscle testing (MMT), physician (MD-GDA), patient (PT-GDA) and extra-muscular global disease activity, HAQ-DI and creatine kinase], SF-36 PF10 and functional tests [six-minute walk, timed up-and-go and sit-to-stand tests] at monthly visits over 6-months. Total improvement score (TIS) using 2016 ACR/EULAR myositis response criteria was obtained as measures of change. RESULTS: Fifty patients [mean age, 51.6; 60% females] were enrolled; 6 PM, 24 DM, 9 NM and 11 with AS. PROMIS PF-20 showed strong test-retest reliability when repeated in 1-month. PROMIS PF-20 had moderate-strong correlations with MD-GDA, PT-GDA, MMT, HAQ-DI, SF-36 PF10, and functional tests indicating good convergent validity. Change in PROMIS PF-20 strongly correlated with TIS demonstrating good responsiveness. HAQ-DI and SF-36 PF10 exhibited similar validity and responsiveness; HAQ-DI was found to have a ceiling effect. CONCLUSION: PROMIS PF-20 demonstrates favorable psychometric properties in a large cohort of myositis patients and offers distinct advantages.

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Published In

Semin Arthritis Rheum

DOI

EISSN

1532-866X

Publication Date

June 2021

Volume

51

Issue

3

Start / End Page

539 / 546

Location

United States

Related Subject Headings

  • Reproducibility of Results
  • Patient Reported Outcome Measures
  • Myositis
  • Middle Aged
  • Male
  • Information Systems
  • Humans
  • Female
  • Arthritis & Rheumatology
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
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Saygin, D., Oddis, C. V., Dzanko, S., Koontz, D., Moghadam-Kia, S., Ardalan, K., … Aggarwal, R. (2021). Utility of patient-reported outcomes measurement information system (PROMIS) physical function form in inflammatory myopathy. Semin Arthritis Rheum, 51(3), 539–546. https://doi.org/10.1016/j.semarthrit.2021.03.018
Saygin, Didem, Chester V. Oddis, Sedin Dzanko, Diane Koontz, Siamak Moghadam-Kia, Kaveh Ardalan, Theresa M. Coles, and Rohit Aggarwal. “Utility of patient-reported outcomes measurement information system (PROMIS) physical function form in inflammatory myopathy.Semin Arthritis Rheum 51, no. 3 (June 2021): 539–46. https://doi.org/10.1016/j.semarthrit.2021.03.018.
Saygin D, Oddis CV, Dzanko S, Koontz D, Moghadam-Kia S, Ardalan K, et al. Utility of patient-reported outcomes measurement information system (PROMIS) physical function form in inflammatory myopathy. Semin Arthritis Rheum. 2021 Jun;51(3):539–46.
Saygin, Didem, et al. “Utility of patient-reported outcomes measurement information system (PROMIS) physical function form in inflammatory myopathy.Semin Arthritis Rheum, vol. 51, no. 3, June 2021, pp. 539–46. Pubmed, doi:10.1016/j.semarthrit.2021.03.018.
Saygin D, Oddis CV, Dzanko S, Koontz D, Moghadam-Kia S, Ardalan K, Coles TM, Aggarwal R. Utility of patient-reported outcomes measurement information system (PROMIS) physical function form in inflammatory myopathy. Semin Arthritis Rheum. 2021 Jun;51(3):539–546.
Journal cover image

Published In

Semin Arthritis Rheum

DOI

EISSN

1532-866X

Publication Date

June 2021

Volume

51

Issue

3

Start / End Page

539 / 546

Location

United States

Related Subject Headings

  • Reproducibility of Results
  • Patient Reported Outcome Measures
  • Myositis
  • Middle Aged
  • Male
  • Information Systems
  • Humans
  • Female
  • Arthritis & Rheumatology
  • Adult