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Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators.

Publication ,  Journal Article
Nduom, EK; Gephart, MH; Chheda, MG; Suva, ML; Amankulor, N; Battiste, JD; Campian, JL; Dacey, RG; Das, S; Fecci, PE; Hadjipanayis, CG; Yang, I ...
Published in: Neurosurgery
June 15, 2021

Patients with glioblastoma (GBM) need bold new approaches to their treatment, yet progress has been hindered by a relative inability to dynamically track treatment response, mechanisms of resistance, evolution of targetable mutations, and changes in mutational burden. We are writing on behalf of a multidisciplinary group of academic neuro-oncology professionals who met at the collaborative Christopher Davidson Forum at Washington University in St Louis in the fall of 2019. We propose a dramatic but necessary change to the routine management of patients with GBM to advance the field: to routinely biopsy recurrent GBM at the time of presumed recurrence. Data derived from these samples will identify true recurrence vs treatment effect, avoid treatments with little chance of success, enable clinical trial access, and aid in the scientific advancement of our understanding of GBM.

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Published In

Neurosurgery

DOI

EISSN

1524-4040

Publication Date

June 15, 2021

Volume

89

Issue

1

Start / End Page

129 / 132

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • Neoplasm Recurrence, Local
  • Mutation
  • Humans
  • Glioblastoma
  • Brain Neoplasms
  • Biopsy
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
 

Citation

APA
Chicago
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MLA
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Nduom, E. K., Gephart, M. H., Chheda, M. G., Suva, M. L., Amankulor, N., Battiste, J. D., … Kim, A. H. (2021). Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators. Neurosurgery, 89(1), 129–132. https://doi.org/10.1093/neuros/nyab063
Nduom, Edjah K., Melanie Hayden Gephart, Milan G. Chheda, Mario L. Suva, Nduka Amankulor, James D. Battiste, Jian L. Campian, et al. “Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators.Neurosurgery 89, no. 1 (June 15, 2021): 129–32. https://doi.org/10.1093/neuros/nyab063.
Nduom EK, Gephart MH, Chheda MG, Suva ML, Amankulor N, Battiste JD, et al. Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators. Neurosurgery. 2021 Jun 15;89(1):129–32.
Nduom, Edjah K., et al. “Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators.Neurosurgery, vol. 89, no. 1, June 2021, pp. 129–32. Pubmed, doi:10.1093/neuros/nyab063.
Nduom EK, Gephart MH, Chheda MG, Suva ML, Amankulor N, Battiste JD, Campian JL, Dacey RG, Das S, Fecci PE, Hadjipanayis CG, Hoang KB, Jalali A, Orringer D, Patel AJ, Placantonakis D, Rodriguez A, Yang I, Yu JS, Zipfel GJ, Dunn GP, Leuthardt EC, Kim AH. Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators. Neurosurgery. 2021 Jun 15;89(1):129–132.
Journal cover image

Published In

Neurosurgery

DOI

EISSN

1524-4040

Publication Date

June 15, 2021

Volume

89

Issue

1

Start / End Page

129 / 132

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • Neoplasm Recurrence, Local
  • Mutation
  • Humans
  • Glioblastoma
  • Brain Neoplasms
  • Biopsy
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences