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Apathy: Neurobiology, assessment and treatment

Publication ,  Journal Article
Fahed, M; Steffens, DC
Published in: Clinical Psychopharmacology and Neuroscience
May 1, 2021

Apathy is a highly prevalent, disabling and treatment resistant syndrome. It is defined as a quantitative reduction of goal-directed activity in comparison to the patient’s previous level of in multiple dimensions including behavior/cognition, emotion and social interaction. It has been described in major depressive disorder, Alzheimer’s disease, frontotemporal dementia, Parkinson’s Disease, cerebrovascular disease, and vascular dementia, among others. This review will address the neuropsychology and associated neurobiological underpinnings of apathy in the above conditions, identify specific methods to assess apathy clinically, and review the literature on managing apathy across these various disorders.

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Published In

Clinical Psychopharmacology and Neuroscience

DOI

EISSN

2093-4327

ISSN

1738-1088

Publication Date

May 1, 2021

Volume

19

Issue

2

Start / End Page

181 / 189

Related Subject Headings

  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Fahed, M., & Steffens, D. C. (2021). Apathy: Neurobiology, assessment and treatment. Clinical Psychopharmacology and Neuroscience, 19(2), 181–189. https://doi.org/10.9758/cpn.2021.19.2.181
Fahed, M., and D. C. Steffens. “Apathy: Neurobiology, assessment and treatment.” Clinical Psychopharmacology and Neuroscience 19, no. 2 (May 1, 2021): 181–89. https://doi.org/10.9758/cpn.2021.19.2.181.
Fahed M, Steffens DC. Apathy: Neurobiology, assessment and treatment. Clinical Psychopharmacology and Neuroscience. 2021 May 1;19(2):181–9.
Fahed, M., and D. C. Steffens. “Apathy: Neurobiology, assessment and treatment.” Clinical Psychopharmacology and Neuroscience, vol. 19, no. 2, May 2021, pp. 181–89. Scopus, doi:10.9758/cpn.2021.19.2.181.
Fahed M, Steffens DC. Apathy: Neurobiology, assessment and treatment. Clinical Psychopharmacology and Neuroscience. 2021 May 1;19(2):181–189.

Published In

Clinical Psychopharmacology and Neuroscience

DOI

EISSN

2093-4327

ISSN

1738-1088

Publication Date

May 1, 2021

Volume

19

Issue

2

Start / End Page

181 / 189

Related Subject Headings

  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences