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Psychological, mobility, and satisfaction variables mediate the relationship between baseline back pain intensity and long-term outcomes in individuals who underwent lumbar spine surgery.

Publication ,  Journal Article
Garcia, AN; Cook, CE; Gottfried, O
Published in: Musculoskelet Sci Pract
October 2021

BACKGROUND: In patients who receive spine surgery, pain is relational to disability and quality of life, but exactly how this influence is mediated is not fully understood. Mediation analyses allow an understanding of a known relationship by exploring the underlying mechanism or processes by which one variable influences another. OBJECTIVES: To determine the mediating influence of psychological, mobility, and satisfaction variables on the relationship between preoperative back pain intensity and 12-month disability and quality of life in individuals who underwent lumbar spine surgery. DESIGN: This mediation analysis study used data from the Quality Outcomes Database (QOD) Lumbar Spine Surgical Registry. METHODS: There were included individuals who received lumbar spine surgery for degenerative spine conditions. The exposure variable was preoperative back pain intensity. Mediator variables were depression/anxiety, mobility, and satisfaction. Outcomes included disability and quality of life. Separate multiple mediator models were conducted using the Hayes PROCESS, Model 4 with bias-corrected bootstrapping (5000 samples) to predict disability and quality of life. RESULTS: 26,130 individuals (n = 13,740 males, mean age 60.2 [SD = 13.8) were included. We observed a significant indirect effect through the mediators (anxiety/depression, mobility and satisfaction), for both disability (b = 0.31, 95%CI = 0.26, 0.35) and quality of life (b = -0.44, 95%CI = -0.48, -0.41). CONCLUSION: Our study suggests that the relationship between preoperative back pain intensity (exposure) and long-term disability and quality of life (outcomes) is partially mediated by anxiety/depression, mobility, and patient satisfaction in individuals who received lumbar spine surgery.

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Published In

Musculoskelet Sci Pract

DOI

EISSN

2468-7812

Publication Date

October 2021

Volume

55

Start / End Page

102424

Location

Netherlands

Related Subject Headings

  • Quality of Life
  • Prospective Studies
  • Personal Satisfaction
  • Middle Aged
  • Male
  • Lumbar Vertebrae
  • Humans
  • Back Pain
 

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Garcia, A. N., Cook, C. E., & Gottfried, O. (2021). Psychological, mobility, and satisfaction variables mediate the relationship between baseline back pain intensity and long-term outcomes in individuals who underwent lumbar spine surgery. Musculoskelet Sci Pract, 55, 102424. https://doi.org/10.1016/j.msksp.2021.102424
Garcia, Alessandra N., Chad E. Cook, and Oren Gottfried. “Psychological, mobility, and satisfaction variables mediate the relationship between baseline back pain intensity and long-term outcomes in individuals who underwent lumbar spine surgery.Musculoskelet Sci Pract 55 (October 2021): 102424. https://doi.org/10.1016/j.msksp.2021.102424.
Garcia, Alessandra N., et al. “Psychological, mobility, and satisfaction variables mediate the relationship between baseline back pain intensity and long-term outcomes in individuals who underwent lumbar spine surgery.Musculoskelet Sci Pract, vol. 55, Oct. 2021, p. 102424. Pubmed, doi:10.1016/j.msksp.2021.102424.
Journal cover image

Published In

Musculoskelet Sci Pract

DOI

EISSN

2468-7812

Publication Date

October 2021

Volume

55

Start / End Page

102424

Location

Netherlands

Related Subject Headings

  • Quality of Life
  • Prospective Studies
  • Personal Satisfaction
  • Middle Aged
  • Male
  • Lumbar Vertebrae
  • Humans
  • Back Pain