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Neuroendocrine Tumor Diagnosis and Management: 68Ga-DOTATATE PET/CT.

Publication ,  Journal Article
Sanli, Y; Garg, I; Kandathil, A; Kendi, T; Zanetti, MJB; Kuyumcu, S; Subramaniam, RM
Published in: AJR Am J Roentgenol
August 2018

OBJECTIVE: The purpose of this article is to provide a review of the use of 68Ga tetraazacyclododecanetetraacetic acid-DPhe1-Tyr3-octreotate (DOTATATE) PET/CT, a functional imaging modality for assessment of well-differentiated neuroendocrine tumors (NETs). It has become the preferred imaging modality for initial diagnosis, selection of patients for peptide receptor radionuclide therapy, and localization of unknown primary tumors. The National Comprehensive Cancer Network guideline has added 68Ga-DOTATATE PET/CT as an appropriate test in the management of NETs. CONCLUSION: In combination with FDG PET/CT, 68Ga-DOTATATE PET/CT can noninvasively assess tumor heterogeneity, especially in G2 and G3 NETs, for personalized management of patients.

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Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

August 2018

Volume

211

Issue

2

Start / End Page

267 / 277

Location

United States

Related Subject Headings

  • Positron Emission Tomography Computed Tomography
  • Organometallic Compounds
  • Nuclear Medicine & Medical Imaging
  • Neuroendocrine Tumors
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
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ICMJE
MLA
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Sanli, Y., Garg, I., Kandathil, A., Kendi, T., Zanetti, M. J. B., Kuyumcu, S., & Subramaniam, R. M. (2018). Neuroendocrine Tumor Diagnosis and Management: 68Ga-DOTATATE PET/CT. AJR Am J Roentgenol, 211(2), 267–277. https://doi.org/10.2214/AJR.18.19881
Sanli, Yasemin, Ishan Garg, Asha Kandathil, Tuba Kendi, Maria J Baladron Zanetti, Serkan Kuyumcu, and Rathan M. Subramaniam. “Neuroendocrine Tumor Diagnosis and Management: 68Ga-DOTATATE PET/CT.AJR Am J Roentgenol 211, no. 2 (August 2018): 267–77. https://doi.org/10.2214/AJR.18.19881.
Sanli Y, Garg I, Kandathil A, Kendi T, Zanetti MJB, Kuyumcu S, et al. Neuroendocrine Tumor Diagnosis and Management: 68Ga-DOTATATE PET/CT. AJR Am J Roentgenol. 2018 Aug;211(2):267–77.
Sanli, Yasemin, et al. “Neuroendocrine Tumor Diagnosis and Management: 68Ga-DOTATATE PET/CT.AJR Am J Roentgenol, vol. 211, no. 2, Aug. 2018, pp. 267–77. Pubmed, doi:10.2214/AJR.18.19881.
Sanli Y, Garg I, Kandathil A, Kendi T, Zanetti MJB, Kuyumcu S, Subramaniam RM. Neuroendocrine Tumor Diagnosis and Management: 68Ga-DOTATATE PET/CT. AJR Am J Roentgenol. 2018 Aug;211(2):267–277.

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

August 2018

Volume

211

Issue

2

Start / End Page

267 / 277

Location

United States

Related Subject Headings

  • Positron Emission Tomography Computed Tomography
  • Organometallic Compounds
  • Nuclear Medicine & Medical Imaging
  • Neuroendocrine Tumors
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences