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PET/CT of Dementia.

Publication ,  Journal Article
Zukotynski, K; Kuo, PH; Mikulis, D; Rosa-Neto, P; Strafella, AP; Subramaniam, RM; Black, SE
Published in: AJR Am J Roentgenol
August 2018

OBJECTIVE: In this article, we review the literature on PET/CT in the management of dementia, present evidence for best clinical practices, and discuss recent advances in the field. CONCLUSION: Standard-of-care imaging for dementia includes CT and MRI, primarily for excluding vascular lesions or masses, detecting atrophy, and monitoring disease severity. PET/CT is a powerful functional modality that can differentiate dementia types and influence management. Fluorine-18-FDG PET/CT reveals the spatial pattern of glucose metabolism in the brain. More recently, radiotracers for PET have been developed that bind to amyloid protein, tau protein, and neuroinflammatory markers.

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Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

August 2018

Volume

211

Issue

2

Start / End Page

246 / 259

Location

United States

Related Subject Headings

  • Radiopharmaceuticals
  • Positron Emission Tomography Computed Tomography
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Fluorodeoxyglucose F18
  • Diagnosis, Differential
  • Dementia
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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ICMJE
MLA
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Zukotynski, K., Kuo, P. H., Mikulis, D., Rosa-Neto, P., Strafella, A. P., Subramaniam, R. M., & Black, S. E. (2018). PET/CT of Dementia. AJR Am J Roentgenol, 211(2), 246–259. https://doi.org/10.2214/AJR.18.19822
Zukotynski, Katherine, Phillip H. Kuo, David Mikulis, Pedro Rosa-Neto, Antonio P. Strafella, Rathan M. Subramaniam, and Sandra E. Black. “PET/CT of Dementia.AJR Am J Roentgenol 211, no. 2 (August 2018): 246–59. https://doi.org/10.2214/AJR.18.19822.
Zukotynski K, Kuo PH, Mikulis D, Rosa-Neto P, Strafella AP, Subramaniam RM, et al. PET/CT of Dementia. AJR Am J Roentgenol. 2018 Aug;211(2):246–59.
Zukotynski, Katherine, et al. “PET/CT of Dementia.AJR Am J Roentgenol, vol. 211, no. 2, Aug. 2018, pp. 246–59. Pubmed, doi:10.2214/AJR.18.19822.
Zukotynski K, Kuo PH, Mikulis D, Rosa-Neto P, Strafella AP, Subramaniam RM, Black SE. PET/CT of Dementia. AJR Am J Roentgenol. 2018 Aug;211(2):246–259.

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

August 2018

Volume

211

Issue

2

Start / End Page

246 / 259

Location

United States

Related Subject Headings

  • Radiopharmaceuticals
  • Positron Emission Tomography Computed Tomography
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Fluorodeoxyglucose F18
  • Diagnosis, Differential
  • Dementia
  • 3202 Clinical sciences
  • 1103 Clinical Sciences