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Computed tomography pulmonary angiogram diagnosis of pulmonary embolism.

Publication ,  Journal Article
Subramaniam, RM; Blair, D; Gilbert, K; Sleigh, J; Karalus, N
Published in: Australas Radiol
June 2006

Over the last decade, contrast-enhanced spiral CT has been established as a non-invasive alternative to catheter angiography and is now regarded as the first-line imaging investigation for the diagnosis of pulmonary embolism (PE). The reported sensitivities for the diagnosis of PE of spiral CT vary from 45 to 100% and the specificities vary from 78 to 100%. Prospective outcome studies have shown a high negative predictive value for a single-detector spiral CT for PE. Patients' outcomes were not adversely affected in these studies when anticoagulation was withheld after a negative CT pulmonary angiogram. The main limitation of single-detector spiral CT has been its limited ability to detect isolated subsegmental PE. However, multidetector spiral CT allows evaluation of pulmonary vessels down to sixth-order branches and significantly increases the rate of detection of PE in segmental and subsegmental levels. The interobserver correlations for diagnosis of subsegmental PE with multidetector spiral CT exceed the reproducibility of selective pulmonary angiography. If appropriate equipment is available (multidetector CT), then CT pulmonary angiogram is safe to be used as the first-line imaging investigation for the diagnosis of PE.

Duke Scholars

Published In

Australas Radiol

DOI

ISSN

0004-8461

Publication Date

June 2006

Volume

50

Issue

3

Start / End Page

193 / 200

Location

Australia

Related Subject Headings

  • Tomography, Spiral Computed
  • Sensitivity and Specificity
  • Pulmonary Embolism
  • Predictive Value of Tests
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Contrast Media
  • Angiography
  • Algorithms
  • 3211 Oncology and carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Subramaniam, R. M., Blair, D., Gilbert, K., Sleigh, J., & Karalus, N. (2006). Computed tomography pulmonary angiogram diagnosis of pulmonary embolism. Australas Radiol, 50(3), 193–200. https://doi.org/10.1111/j.1440-1673.2006.01561.x
Subramaniam, R. M., D. Blair, K. Gilbert, J. Sleigh, and N. Karalus. “Computed tomography pulmonary angiogram diagnosis of pulmonary embolism.Australas Radiol 50, no. 3 (June 2006): 193–200. https://doi.org/10.1111/j.1440-1673.2006.01561.x.
Subramaniam RM, Blair D, Gilbert K, Sleigh J, Karalus N. Computed tomography pulmonary angiogram diagnosis of pulmonary embolism. Australas Radiol. 2006 Jun;50(3):193–200.
Subramaniam, R. M., et al. “Computed tomography pulmonary angiogram diagnosis of pulmonary embolism.Australas Radiol, vol. 50, no. 3, June 2006, pp. 193–200. Pubmed, doi:10.1111/j.1440-1673.2006.01561.x.
Subramaniam RM, Blair D, Gilbert K, Sleigh J, Karalus N. Computed tomography pulmonary angiogram diagnosis of pulmonary embolism. Australas Radiol. 2006 Jun;50(3):193–200.
Journal cover image

Published In

Australas Radiol

DOI

ISSN

0004-8461

Publication Date

June 2006

Volume

50

Issue

3

Start / End Page

193 / 200

Location

Australia

Related Subject Headings

  • Tomography, Spiral Computed
  • Sensitivity and Specificity
  • Pulmonary Embolism
  • Predictive Value of Tests
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Contrast Media
  • Angiography
  • Algorithms
  • 3211 Oncology and carcinogenesis