Cardiac Manifestations of Multisystem Inflammatory Syndrome in Children (MIS-C) Following COVID-19.
PURPOSE OF REVIEW: To review the spectrum of cardiac manifestations and treatments of multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19). RECENT FINDINGS: Studies demonstrate that up to 80% of children with MIS-C may have cardiac involvement on a spectrum of severity. Cardiac manifestations include myocarditis, coronary artery aneurysms, conduction abnormalities, and arrhythmias. Current treatments, including inotropic support, immunomodulatory therapy, and anti-coagulation, have been effective at resolving these cardiac findings in the majority of patients. COVID-19 can also cause myocarditis in the acute stage of illness and recent descriptions of COVID-19 vaccine myocarditis have occurred. Cardiac manifestations are common in MIS-C and should be assessed for at presentation and during the clinical course as indicated.
Duke Scholars
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Related Subject Headings
- Systemic Inflammatory Response Syndrome
- SARS-CoV-2
- Humans
- Cardiovascular System & Hematology
- COVID-19 Vaccines
- COVID-19
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Systemic Inflammatory Response Syndrome
- SARS-CoV-2
- Humans
- Cardiovascular System & Hematology
- COVID-19 Vaccines
- COVID-19
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology