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Persistent fatigue among long-term non-Hodgkin lymphoma survivors.

Publication ,  Journal Article
LeBlanc, MR; Zimmerman, S; LeBlanc, TW; Bryant, AL; Hudson, KE; Smith, SK
Published in: Leuk Lymphoma
February 2022

This study describes the prevalence and persistence of fatigue among a cohort of long-term non-Hodgkin lymphoma (NHL) survivors. Mailed surveys assessed quality-of-life including fatigue (SF-36) at baseline and five years. Logistic regression was used to identify factors associated with prevalence of fatigue at baseline and persistence of fatigue across timepoints. More than one-quarter (27.7%) of the 555 NHL survivors reported clinically meaningful fatigue at baseline and 18.7% reported persistent fatigue at five years. One-third (34.4%) reported clinically meaningful worsening of fatigue over time. Independent associations with persistent fatigue included female gender, less education, past chemotherapy, increased comorbidities, and posttraumatic stress symptoms (P <.05). Our findings suggest that one in three NHL survivors experience clinically meaningful fatigue long after their diagnosis and initial treatment. Furthermore, we found that fatigue worsens or persists for many, highlighting the need for vigilance in assessing and treating fatigue in this population.

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Published In

Leuk Lymphoma

DOI

EISSN

1029-2403

Publication Date

February 2022

Volume

63

Issue

2

Start / End Page

344 / 352

Location

United States

Related Subject Headings

  • Survivors
  • Surveys and Questionnaires
  • Quality of Life
  • Lymphoma, Non-Hodgkin
  • Immunology
  • Humans
  • Female
  • Fatigue
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
LeBlanc, M. R., Zimmerman, S., LeBlanc, T. W., Bryant, A. L., Hudson, K. E., & Smith, S. K. (2022). Persistent fatigue among long-term non-Hodgkin lymphoma survivors. Leuk Lymphoma, 63(2), 344–352. https://doi.org/10.1080/10428194.2021.1984450
LeBlanc, Matthew R., Sheryl Zimmerman, Thomas W. LeBlanc, Ashley Leak Bryant, Kathryn E. Hudson, and Sophia K. Smith. “Persistent fatigue among long-term non-Hodgkin lymphoma survivors.Leuk Lymphoma 63, no. 2 (February 2022): 344–52. https://doi.org/10.1080/10428194.2021.1984450.
LeBlanc MR, Zimmerman S, LeBlanc TW, Bryant AL, Hudson KE, Smith SK. Persistent fatigue among long-term non-Hodgkin lymphoma survivors. Leuk Lymphoma. 2022 Feb;63(2):344–52.
LeBlanc, Matthew R., et al. “Persistent fatigue among long-term non-Hodgkin lymphoma survivors.Leuk Lymphoma, vol. 63, no. 2, Feb. 2022, pp. 344–52. Pubmed, doi:10.1080/10428194.2021.1984450.
LeBlanc MR, Zimmerman S, LeBlanc TW, Bryant AL, Hudson KE, Smith SK. Persistent fatigue among long-term non-Hodgkin lymphoma survivors. Leuk Lymphoma. 2022 Feb;63(2):344–352.

Published In

Leuk Lymphoma

DOI

EISSN

1029-2403

Publication Date

February 2022

Volume

63

Issue

2

Start / End Page

344 / 352

Location

United States

Related Subject Headings

  • Survivors
  • Surveys and Questionnaires
  • Quality of Life
  • Lymphoma, Non-Hodgkin
  • Immunology
  • Humans
  • Female
  • Fatigue
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences