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Anaphylactic Reaction to Lymphazurin 1% during Breast Reconstruction Surgery: An Uncommon but Serious Complication.

Publication ,  Journal Article
Krishna, V; Muetterties, C; DiNome, ML; Tseng, CY
Published in: Plast Reconstr Surg Glob Open
September 2020

Lymphazurin 1% (isosulfan blue dye) is the most frequently used blue dye in the United States, and it is commonly used for sentinel node biopsy in breast cancer patients. Although cases of allergic reaction to lymphazurin have been reported in the general surgery literature, to our knowledge, no cases of an adverse reaction to isosulfan blue have been reported in the plastic surgery literature. We describe a case of an intraoperative biphasic anaphylactic reaction to isosulfan blue in a female patient undergoing bilateral mastectomy and immediate bilateral DIEP breast reconstruction. The severity of her anaphylactic reaction required that we stop flap dissection and abort the reconstruction. Although an allergic reaction is uncommon, recognizing the signs of an acute hypersensitivity reaction is critical to good outcomes in these situations. Given the volume of combined breast oncologic and breast reconstruction surgeries and the increasing number of vascularized lymph node transfer and lymphovenous anastomosis performed annually, it is essential for the plastic surgeon to be cognizant of this rare hypersensitivity reaction.

Duke Scholars

Published In

Plast Reconstr Surg Glob Open

DOI

ISSN

2169-7574

Publication Date

September 2020

Volume

8

Issue

9

Start / End Page

e3075

Location

United States

Related Subject Headings

  • 3213 Paediatrics
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Krishna, V., Muetterties, C., DiNome, M. L., & Tseng, C. Y. (2020). Anaphylactic Reaction to Lymphazurin 1% during Breast Reconstruction Surgery: An Uncommon but Serious Complication. Plast Reconstr Surg Glob Open, 8(9), e3075. https://doi.org/10.1097/GOX.0000000000003075
Krishna, Vikram, Corbin Muetterties, Maggie L. DiNome, and Charles Y. Tseng. “Anaphylactic Reaction to Lymphazurin 1% during Breast Reconstruction Surgery: An Uncommon but Serious Complication.Plast Reconstr Surg Glob Open 8, no. 9 (September 2020): e3075. https://doi.org/10.1097/GOX.0000000000003075.
Krishna V, Muetterties C, DiNome ML, Tseng CY. Anaphylactic Reaction to Lymphazurin 1% during Breast Reconstruction Surgery: An Uncommon but Serious Complication. Plast Reconstr Surg Glob Open. 2020 Sep;8(9):e3075.
Krishna, Vikram, et al. “Anaphylactic Reaction to Lymphazurin 1% during Breast Reconstruction Surgery: An Uncommon but Serious Complication.Plast Reconstr Surg Glob Open, vol. 8, no. 9, Sept. 2020, p. e3075. Pubmed, doi:10.1097/GOX.0000000000003075.
Krishna V, Muetterties C, DiNome ML, Tseng CY. Anaphylactic Reaction to Lymphazurin 1% during Breast Reconstruction Surgery: An Uncommon but Serious Complication. Plast Reconstr Surg Glob Open. 2020 Sep;8(9):e3075.

Published In

Plast Reconstr Surg Glob Open

DOI

ISSN

2169-7574

Publication Date

September 2020

Volume

8

Issue

9

Start / End Page

e3075

Location

United States

Related Subject Headings

  • 3213 Paediatrics
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences