Skip to main content
Journal cover image

The role of normal nasal morphological variations from race and gender differences on respiratory physiology.

Publication ,  Journal Article
Shah, R; Frank-Ito, DO
Published in: Respir Physiol Neurobiol
March 2022

This study identifies anatomical and airflow-induced relationships based on nasal morphological variations due to inter- and intra-racial differences and gender. Subject-specific nasal airway reconstruction was created from computed tomography images in 16 subjects: 4 subjects from each ethnic group (Black, East Asian, Caucasian, and Latino) comprising of 2 males and 2 females. Volume, surface area and nasal index were calculated, as well as airflow rate and nasal resistance after computational fluid dynamics simulations in the nasal airway. Results showed that nasal airspace surface area (p = 0.0499) and volume (p = 0.0281) were significantly greater in males than in females. Nasal volume was greatest in East Asians (Median = 20.38cm3, Interquartile Range [IQR] = 4.58 cm3), Latinos had the greatest surface area (Median = 219.70cm2, IQR = 29.56cm2). On average, East Asian and Black females had larger nasal index than their male counterparts. Caucasians had the highest median nasal resistance (0.050 Pa.s/mL, IQR = 0.025 Pa.s/mL). Results indicate that there exist anatomical variabilities based on race and gender. However, these variabilities may not significantly influence nasal function.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Respir Physiol Neurobiol

DOI

EISSN

1878-1519

Publication Date

March 2022

Volume

297

Start / End Page

103823

Location

Netherlands

Related Subject Headings

  • White People
  • United States
  • Sex Characteristics
  • Respiratory Physiological Phenomena
  • Physiology
  • Nasal Cavity
  • Models, Theoretical
  • Male
  • Humans
  • Hispanic or Latino
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Shah, R., & Frank-Ito, D. O. (2022). The role of normal nasal morphological variations from race and gender differences on respiratory physiology. Respir Physiol Neurobiol, 297, 103823. https://doi.org/10.1016/j.resp.2021.103823
Shah, Reanna, and Dennis Onyeka Frank-Ito. “The role of normal nasal morphological variations from race and gender differences on respiratory physiology.Respir Physiol Neurobiol 297 (March 2022): 103823. https://doi.org/10.1016/j.resp.2021.103823.
Shah, Reanna, and Dennis Onyeka Frank-Ito. “The role of normal nasal morphological variations from race and gender differences on respiratory physiology.Respir Physiol Neurobiol, vol. 297, Mar. 2022, p. 103823. Pubmed, doi:10.1016/j.resp.2021.103823.
Journal cover image

Published In

Respir Physiol Neurobiol

DOI

EISSN

1878-1519

Publication Date

March 2022

Volume

297

Start / End Page

103823

Location

Netherlands

Related Subject Headings

  • White People
  • United States
  • Sex Characteristics
  • Respiratory Physiological Phenomena
  • Physiology
  • Nasal Cavity
  • Models, Theoretical
  • Male
  • Humans
  • Hispanic or Latino