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International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins.

Publication ,  Journal Article
Tan, PH; Cheng, L; Srigley, JR; Griffiths, D; Humphrey, PA; van der Kwast, TH; Montironi, R; Wheeler, TM; Delahunt, B; Egevad, L; Epstein, JI ...
Published in: Mod Pathol
January 2011

The 2009 International Society of Urological Pathology Consensus Conference in Boston, made recommendations regarding the standardization of pathology reporting of radical prostatectomy specimens. Issues relating to surgical margin assessment were coordinated by working group 5. Pathologists agreed that tumor extending close to the 'capsular' margin, yet not to it, should be reported as a negative margin, and that locations of positive margins should be indicated as either posterior, posterolateral, lateral, anterior at the prostatic apex, mid-prostate or base. Other items of consensus included specifying the extent of any positive margin as millimeters of involvement; tumor in skeletal muscle at the apical perpendicular margin section, in the absence of accompanying benign glands, to be considered organ confined; and that proximal and distal margins be uniformly referred to as bladder neck and prostatic apex, respectively. Grading of tumor at positive margins was to be left to the discretion of the reporting pathologists. There was no consensus as to how the surgical margin should be regarded when tumor is present at the inked edge of the tissue, in the absence of transected benign glands at the apical margin. Pathologists also did not achieve agreement on the reporting approach to benign prostatic glands at an inked surgical margin in which no carcinoma is present.

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Published In

Mod Pathol

DOI

EISSN

1530-0285

Publication Date

January 2011

Volume

24

Issue

1

Start / End Page

48 / 57

Location

United States

Related Subject Headings

  • Urinary Bladder
  • Specimen Handling
  • Societies, Medical
  • Prostatic Neoplasms
  • Prostatectomy
  • Pathology
  • Neoplasm Staging
  • Male
  • Humans
  • Adenocarcinoma
 

Citation

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Tan, P. H., Cheng, L., Srigley, J. R., Griffiths, D., Humphrey, P. A., van der Kwast, T. H., … ISUP Prostate Cancer Group, . (2011). International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins. Mod Pathol, 24(1), 48–57. https://doi.org/10.1038/modpathol.2010.155
Tan, Puay Hoon, Liang Cheng, John R. Srigley, David Griffiths, Peter A. Humphrey, Theodore H. van der Kwast, Rodolfo Montironi, et al. “International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins.Mod Pathol 24, no. 1 (January 2011): 48–57. https://doi.org/10.1038/modpathol.2010.155.
Tan PH, Cheng L, Srigley JR, Griffiths D, Humphrey PA, van der Kwast TH, et al. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins. Mod Pathol. 2011 Jan;24(1):48–57.
Tan, Puay Hoon, et al. “International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins.Mod Pathol, vol. 24, no. 1, Jan. 2011, pp. 48–57. Pubmed, doi:10.1038/modpathol.2010.155.
Tan PH, Cheng L, Srigley JR, Griffiths D, Humphrey PA, van der Kwast TH, Montironi R, Wheeler TM, Delahunt B, Egevad L, Epstein JI, ISUP Prostate Cancer Group. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins. Mod Pathol. 2011 Jan;24(1):48–57.

Published In

Mod Pathol

DOI

EISSN

1530-0285

Publication Date

January 2011

Volume

24

Issue

1

Start / End Page

48 / 57

Location

United States

Related Subject Headings

  • Urinary Bladder
  • Specimen Handling
  • Societies, Medical
  • Prostatic Neoplasms
  • Prostatectomy
  • Pathology
  • Neoplasm Staging
  • Male
  • Humans
  • Adenocarcinoma