Skip to main content
Journal cover image

Determinants and Trends of COVID-19 Vaccine Hesitancy and Vaccine Uptake in a National Cohort of US Adults: A Longitudinal Study.

Publication ,  Journal Article
Rane, MS; Kochhar, S; Poehlein, E; You, W; Robertson, MM; Zimba, R; Westmoreland, DA; Romo, ML; Kulkarni, SG; Chang, M; Berry, A; Maroko, AR ...
Published in: American journal of epidemiology
March 2022

We estimated the trends and correlates of vaccine hesitancy and its association with subsequent vaccine uptake among 5,458 adults in the United States. Participants belonged to the Communities, Households, and SARS-CoV-2 Epidemiology COVID (CHASING COVID) Cohort, a national longitudinal study. Trends and correlates of vaccine hesitancy were examined longitudinally in 8 interview rounds from October 2020 to July 2021. We also estimated the association between willingness to vaccinate and subsequent vaccine uptake through July 2021. Vaccine delay and refusal decreased from 51% and 8% in October 2020 to 8% and 6% in July 2021, respectively. Compared with non-Hispanic (NH) White participants, NH Black and Hispanic participants had higher adjusted odds ratios (aOR) for both vaccine delay (for NH Black, aOR = 2.0 (95% confidence interval (CI): 1.5, 2.7), and for Hispanic, 1.3 (95% CI: 1.0, 1.7)) and vaccine refusal (for NH Black, aOR = 2.5 (95% CI: 1.8, 3.6), and for Hispanic, 1.4 (95% CI: 1.0, 2.0)) in June 2021. COVID-19 vaccine hesitancy, compared with vaccine-willingness, was associated with lower odds of subsequent vaccine uptake (for vaccine delayers, aOR = 0.15, 95% CI: 0.13, 0.18; for vaccine refusers, aOR = 0.02; 95% CI: 0.01, 0.03 ), adjusted for sociodemographic factors and COVID-19 history. Vaccination awareness and distribution efforts should focus on vaccine delayers.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

American journal of epidemiology

DOI

EISSN

1476-6256

ISSN

0002-9262

Publication Date

March 2022

Volume

191

Issue

4

Start / End Page

570 / 583

Related Subject Headings

  • Vaccines
  • Vaccination Hesitancy
  • Vaccination
  • United States
  • SARS-CoV-2
  • Longitudinal Studies
  • Humans
  • Epidemiology
  • COVID-19 Vaccines
  • COVID-19
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Rane, M. S., Kochhar, S., Poehlein, E., You, W., Robertson, M. M., Zimba, R., … CHASING COVID Cohort Study Team, . (2022). Determinants and Trends of COVID-19 Vaccine Hesitancy and Vaccine Uptake in a National Cohort of US Adults: A Longitudinal Study. American Journal of Epidemiology, 191(4), 570–583. https://doi.org/10.1093/aje/kwab293
Rane, Madhura S., Shivani Kochhar, Emily Poehlein, William You, McKaylee M. Robertson, Rebecca Zimba, Drew A. Westmoreland, et al. “Determinants and Trends of COVID-19 Vaccine Hesitancy and Vaccine Uptake in a National Cohort of US Adults: A Longitudinal Study.American Journal of Epidemiology 191, no. 4 (March 2022): 570–83. https://doi.org/10.1093/aje/kwab293.
Rane MS, Kochhar S, Poehlein E, You W, Robertson MM, Zimba R, et al. Determinants and Trends of COVID-19 Vaccine Hesitancy and Vaccine Uptake in a National Cohort of US Adults: A Longitudinal Study. American journal of epidemiology. 2022 Mar;191(4):570–83.
Rane, Madhura S., et al. “Determinants and Trends of COVID-19 Vaccine Hesitancy and Vaccine Uptake in a National Cohort of US Adults: A Longitudinal Study.American Journal of Epidemiology, vol. 191, no. 4, Mar. 2022, pp. 570–83. Epmc, doi:10.1093/aje/kwab293.
Rane MS, Kochhar S, Poehlein E, You W, Robertson MM, Zimba R, Westmoreland DA, Romo ML, Kulkarni SG, Chang M, Berry A, Parcesepe AM, Maroko AR, Grov C, Nash D, CHASING COVID Cohort Study Team. Determinants and Trends of COVID-19 Vaccine Hesitancy and Vaccine Uptake in a National Cohort of US Adults: A Longitudinal Study. American journal of epidemiology. 2022 Mar;191(4):570–583.
Journal cover image

Published In

American journal of epidemiology

DOI

EISSN

1476-6256

ISSN

0002-9262

Publication Date

March 2022

Volume

191

Issue

4

Start / End Page

570 / 583

Related Subject Headings

  • Vaccines
  • Vaccination Hesitancy
  • Vaccination
  • United States
  • SARS-CoV-2
  • Longitudinal Studies
  • Humans
  • Epidemiology
  • COVID-19 Vaccines
  • COVID-19