Biomarkers of toxicity in zebrafish

Given that zebrafish have now become an accepted model for toxicological studies in both the human health and ecological communities, this chapter takes stock of the status of biomarkers of toxicity that have been proposed for the zebrafish model. Most of what is discussed here are biomarkers of effect, but the line between biomarkers of effect and exposure is often not well defined. Generally the chapter strives to present examples of many different types of biomarkers for many classes of toxicological "icities," but the chapter is not a comprehensive survey of all the zebrafish biomarker literature. Rather, it is a critical appraisal of the state of the effort to develop and identify biomarkers of toxicity in zebrafish. © 2014 Elsevier Inc. All rights reserved.

Duke Scholars

Author Stephanie Padilla Environmental Sciences and Policy