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Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizations.

Publication ,  Journal Article
Eliades, SJ; Wang, X
Published in: J Neurophysiol
April 2003

Little is known about sensory-motor interaction in the auditory cortex of primates at the level of single neurons and its role in supporting vocal communication. The present study investigated single-unit activities in the auditory cortex of a vocal primate, the common marmoset (Callithrix jacchus), during self-initiated vocalizations. We found that 1) self-initiated vocalizations resulted in suppression of neural discharges in a majority of auditory cortical neurons. The vocalization-induced inhibition suppressed both spontaneous and stimulus-driven discharges. Suppressed units responded poorly to external acoustic stimuli during vocalization. 2) Vocalization-induced suppression began several hundred milliseconds prior to the onset of vocalization. 3) The suppression of cortical discharges reduced neural firings to below the rates expected from a unit's rate-level function, adjusted for known subcortical attenuation, and therefore was likely not entirely caused by subcortical attenuation mechanisms. 4) A smaller population of auditory cortical neurons showed increased discharges during self-initiated vocalizations. This vocalization-related excitation began after the onset of vocalization and is likely the result of acoustic feedback. Units showing this excitation responded nearly normally to external stimuli during vocalization. Based on these findings, we propose that the suppression of auditory cortical neurons, possibly originating from cortical vocal production centers, acts to increase the dynamic range of cortical responses to vocalization feedback for self monitoring. The excitatory responses, on the other hand, likely play a role in maintaining hearing sensitivity to the external acoustic environment during vocalization.

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Published In

J Neurophysiol

DOI

ISSN

0022-3077

Publication Date

April 2003

Volume

89

Issue

4

Start / End Page

2194 / 2207

Location

United States

Related Subject Headings

  • Vocalization, Animal
  • Neurons, Afferent
  • Neurology & Neurosurgery
  • Neural Pathways
  • Motor Neurons
  • Feedback
  • Electrophysiology
  • Callithrix
  • Auditory Cortex
  • Animals
 

Citation

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Eliades, S. J., & Wang, X. (2003). Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizations. J Neurophysiol, 89(4), 2194–2207. https://doi.org/10.1152/jn.00627.2002
Eliades, Steven J., and Xiaoqin Wang. “Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizations.J Neurophysiol 89, no. 4 (April 2003): 2194–2207. https://doi.org/10.1152/jn.00627.2002.
Eliades SJ, Wang X. Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizations. J Neurophysiol. 2003 Apr;89(4):2194–207.
Eliades, Steven J., and Xiaoqin Wang. “Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizations.J Neurophysiol, vol. 89, no. 4, Apr. 2003, pp. 2194–207. Pubmed, doi:10.1152/jn.00627.2002.
Eliades SJ, Wang X. Sensory-motor interaction in the primate auditory cortex during self-initiated vocalizations. J Neurophysiol. 2003 Apr;89(4):2194–2207.

Published In

J Neurophysiol

DOI

ISSN

0022-3077

Publication Date

April 2003

Volume

89

Issue

4

Start / End Page

2194 / 2207

Location

United States

Related Subject Headings

  • Vocalization, Animal
  • Neurons, Afferent
  • Neurology & Neurosurgery
  • Neural Pathways
  • Motor Neurons
  • Feedback
  • Electrophysiology
  • Callithrix
  • Auditory Cortex
  • Animals