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Haematological cancer: Richter's transformation in CLL-a distinct lymphoma.

Publication ,  Journal Article
Jain, P; Young, KH
Published in: Nat Rev Clin Oncol
January 2014

A landmark study has delineated and identified the genetic pathways that drive the natural course of chronic lymphocytic leukaemia (CLL) B cells into Richter’s transformation. CLL-related Richter’s transformation is a distinct lymphoma, and poses various questions about B-cell ontogeny and relevance of B cell receptor signalling inhibitors.

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Published In

Nat Rev Clin Oncol

DOI

EISSN

1759-4782

Publication Date

January 2014

Volume

11

Issue

1

Start / End Page

6 / 8

Location

England

Related Subject Headings

  • Signal Transduction
  • Receptors, Antigen, B-Cell
  • Pre-B Cell Receptors
  • Lymphoma, Large B-Cell, Diffuse
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Humans
  • Cell Transformation, Neoplastic
  • Antineoplastic Agents
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

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ICMJE
MLA
NLM
Jain, P., & Young, K. H. (2014). Haematological cancer: Richter's transformation in CLL-a distinct lymphoma. Nat Rev Clin Oncol, 11(1), 6–8. https://doi.org/10.1038/nrclinonc.2013.229
Jain, Preetesh, and Ken H. Young. “Haematological cancer: Richter's transformation in CLL-a distinct lymphoma.Nat Rev Clin Oncol 11, no. 1 (January 2014): 6–8. https://doi.org/10.1038/nrclinonc.2013.229.
Jain P, Young KH. Haematological cancer: Richter's transformation in CLL-a distinct lymphoma. Nat Rev Clin Oncol. 2014 Jan;11(1):6–8.
Jain, Preetesh, and Ken H. Young. “Haematological cancer: Richter's transformation in CLL-a distinct lymphoma.Nat Rev Clin Oncol, vol. 11, no. 1, Jan. 2014, pp. 6–8. Pubmed, doi:10.1038/nrclinonc.2013.229.
Jain P, Young KH. Haematological cancer: Richter's transformation in CLL-a distinct lymphoma. Nat Rev Clin Oncol. 2014 Jan;11(1):6–8.

Published In

Nat Rev Clin Oncol

DOI

EISSN

1759-4782

Publication Date

January 2014

Volume

11

Issue

1

Start / End Page

6 / 8

Location

England

Related Subject Headings

  • Signal Transduction
  • Receptors, Antigen, B-Cell
  • Pre-B Cell Receptors
  • Lymphoma, Large B-Cell, Diffuse
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Humans
  • Cell Transformation, Neoplastic
  • Antineoplastic Agents
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis