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Role of stereotactic body radiotherapy in gynecologic radiation oncology.

Publication ,  Journal Article
Shenker, R; Stephens, SJ; Davidson, B; Chino, J
Published in: Int J Gynecol Cancer
March 2022

Stereotactic body radiotherapy (SBRT, also referred to as stereotactic ablative radiotherapy (SABR)) has been used in the treatment of primary and metastatic solid tumors, and increasingly so in gynecologic oncology. This review article aims to summarize the current literature describing the utility of SBRT in the primary, recurrent, and limited metastatic settings for gynecologic malignancies. The use of SBRT in both retrospective and prospective reports has been associated with adequate control of the treated site, particularly in the setting of oligometastatic disease. It is not, however, recommended as an alternative to brachytherapy for intact disease unless all efforts to use brachytherapy are exhausted. While phase I and II trials have established the relative safety and potential toxicities of SBRT, there remains a dearth of phase III randomized evidence, including the use of immunotherapy, in order to better establish the role of this technique as a method of improving more global outcomes for our patients with gynecologic cancers.

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Published In

Int J Gynecol Cancer

DOI

EISSN

1525-1438

Publication Date

March 2022

Volume

32

Issue

3

Start / End Page

372 / 379

Location

England

Related Subject Headings

  • Retrospective Studies
  • Radiosurgery
  • Radiation Oncology
  • Prospective Studies
  • Oncology & Carcinogenesis
  • Humans
  • Genital Neoplasms, Female
  • Female
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences
 

Citation

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Shenker, R., Stephens, S. J., Davidson, B., & Chino, J. (2022). Role of stereotactic body radiotherapy in gynecologic radiation oncology. Int J Gynecol Cancer, 32(3), 372–379. https://doi.org/10.1136/ijgc-2021-002466
Shenker, Rachel, Sarah J. Stephens, Brittany Davidson, and Junzo Chino. “Role of stereotactic body radiotherapy in gynecologic radiation oncology.Int J Gynecol Cancer 32, no. 3 (March 2022): 372–79. https://doi.org/10.1136/ijgc-2021-002466.
Shenker R, Stephens SJ, Davidson B, Chino J. Role of stereotactic body radiotherapy in gynecologic radiation oncology. Int J Gynecol Cancer. 2022 Mar;32(3):372–9.
Shenker, Rachel, et al. “Role of stereotactic body radiotherapy in gynecologic radiation oncology.Int J Gynecol Cancer, vol. 32, no. 3, Mar. 2022, pp. 372–79. Pubmed, doi:10.1136/ijgc-2021-002466.
Shenker R, Stephens SJ, Davidson B, Chino J. Role of stereotactic body radiotherapy in gynecologic radiation oncology. Int J Gynecol Cancer. 2022 Mar;32(3):372–379.
Journal cover image

Published In

Int J Gynecol Cancer

DOI

EISSN

1525-1438

Publication Date

March 2022

Volume

32

Issue

3

Start / End Page

372 / 379

Location

England

Related Subject Headings

  • Retrospective Studies
  • Radiosurgery
  • Radiation Oncology
  • Prospective Studies
  • Oncology & Carcinogenesis
  • Humans
  • Genital Neoplasms, Female
  • Female
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences