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Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast.

Publication ,  Journal Article
Roussin-Léveillée, C; Lajeunesse, G; St-Amand, M; Veerapen, VP; Silva-Martins, G; Nomura, K; Brassard, S; Bolaji, A; He, SY; Moffett, P
Published in: Cell host & microbe
April 2022

High atmospheric humidity levels profoundly impact host-pathogen interactions in plants by enabling the establishment of an aqueous living space that benefits pathogens. The effectors HopM1 and AvrE1 of the bacterial pathogen Pseudomonas syringae have been shown to induce an aqueous apoplast under such conditions. However, the mechanisms by which this happens remain unknown. Here, we show that HopM1 and AvrE1 work redundantly to establish an aqueous living space by inducing a major reprogramming of the Arabidopsis thaliana transcriptome landscape. These effectors induce a strong abscisic acid (ABA) signature, which promotes stomatal closure, resulting in reduced leaf transpiration and water-soaking lesions. Furthermore, these effectors preferentially increase ABA accumulation in guard cells, which control stomatal aperture. Notably, a guard-cell-specific ABA transporter, ABCG40, is necessary for HopM1 induction of water-soaking lesions. This study provides molecular insights into a chain of events of stomatal manipulation that create an ideal microenvironment to facilitate infection.

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Published In

Cell host & microbe

DOI

EISSN

1934-6069

ISSN

1931-3128

Publication Date

April 2022

Volume

30

Issue

4

Start / End Page

489 / 501.e4

Related Subject Headings

  • Water
  • Pseudomonas syringae
  • Plant Stomata
  • Immunology
  • Arabidopsis Proteins
  • Arabidopsis
  • Abscisic Acid
  • 3207 Medical microbiology
  • 3107 Microbiology
  • 3101 Biochemistry and cell biology
 

Citation

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Roussin-Léveillée, C., Lajeunesse, G., St-Amand, M., Veerapen, V. P., Silva-Martins, G., Nomura, K., … Moffett, P. (2022). Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast. Cell Host & Microbe, 30(4), 489-501.e4. https://doi.org/10.1016/j.chom.2022.02.006
Roussin-Léveillée, Charles, Gaële Lajeunesse, Méliane St-Amand, Varusha Pillay Veerapen, Guilherme Silva-Martins, Kinya Nomura, Sandrine Brassard, Ayooluwa Bolaji, Sheng Yang He, and Peter Moffett. “Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast.Cell Host & Microbe 30, no. 4 (April 2022): 489-501.e4. https://doi.org/10.1016/j.chom.2022.02.006.
Roussin-Léveillée C, Lajeunesse G, St-Amand M, Veerapen VP, Silva-Martins G, Nomura K, et al. Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast. Cell host & microbe. 2022 Apr;30(4):489-501.e4.
Roussin-Léveillée, Charles, et al. “Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast.Cell Host & Microbe, vol. 30, no. 4, Apr. 2022, pp. 489-501.e4. Epmc, doi:10.1016/j.chom.2022.02.006.
Roussin-Léveillée C, Lajeunesse G, St-Amand M, Veerapen VP, Silva-Martins G, Nomura K, Brassard S, Bolaji A, He SY, Moffett P. Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast. Cell host & microbe. 2022 Apr;30(4):489-501.e4.
Journal cover image

Published In

Cell host & microbe

DOI

EISSN

1934-6069

ISSN

1931-3128

Publication Date

April 2022

Volume

30

Issue

4

Start / End Page

489 / 501.e4

Related Subject Headings

  • Water
  • Pseudomonas syringae
  • Plant Stomata
  • Immunology
  • Arabidopsis Proteins
  • Arabidopsis
  • Abscisic Acid
  • 3207 Medical microbiology
  • 3107 Microbiology
  • 3101 Biochemistry and cell biology