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Recent Advances in 1,2-Amino(hetero)arylation of Alkenes.

Publication ,  Journal Article
Kwon, Y; Wang, Q
Published in: Chemistry, an Asian journal
June 2022

Alkene amino(hetero)arylation presents a highly efficient and straightforward strategy for direct installation of amino groups and heteroaryl rings across a double bond simultaneously. An extensive array of practical transformations has been developed via alkene difunctionalization approach to access a broad range of medicinally valuable (hetero)arylethylamine motifs. This review presents recent progress in 1,2-amino(hetero)arylation of alkenes organized in three different modes. First, intramolecular transformations employing C, N-tethered alkenes will be introduced. Next, two-component reactions will be discussed with different combination of precursors, N-tethered alkenes and external aryl precursor, C-tethered alkenes and external amine precursor, or C, N-tethered reagents, and alkenes. Last, three-component intermolecular amino(hetero)arylation reactions will be covered.

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Published In

Chemistry, an Asian journal

DOI

EISSN

1861-471X

ISSN

1861-4728

Publication Date

June 2022

Volume

17

Issue

12

Start / End Page

e202200215

Related Subject Headings

  • General Chemistry
  • Catalysis
  • Amines
  • Amination
  • Alkenes
  • 34 Chemical sciences
  • 03 Chemical Sciences
 

Citation

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Kwon, Y., & Wang, Q. (2022). Recent Advances in 1,2-Amino(hetero)arylation of Alkenes. Chemistry, an Asian Journal, 17(12), e202200215. https://doi.org/10.1002/asia.202200215
Kwon, Yungeun, and Qiu Wang. “Recent Advances in 1,2-Amino(hetero)arylation of Alkenes.Chemistry, an Asian Journal 17, no. 12 (June 2022): e202200215. https://doi.org/10.1002/asia.202200215.
Kwon Y, Wang Q. Recent Advances in 1,2-Amino(hetero)arylation of Alkenes. Chemistry, an Asian journal. 2022 Jun;17(12):e202200215.
Kwon, Yungeun, and Qiu Wang. “Recent Advances in 1,2-Amino(hetero)arylation of Alkenes.Chemistry, an Asian Journal, vol. 17, no. 12, June 2022, p. e202200215. Epmc, doi:10.1002/asia.202200215.
Kwon Y, Wang Q. Recent Advances in 1,2-Amino(hetero)arylation of Alkenes. Chemistry, an Asian journal. 2022 Jun;17(12):e202200215.
Journal cover image

Published In

Chemistry, an Asian journal

DOI

EISSN

1861-471X

ISSN

1861-4728

Publication Date

June 2022

Volume

17

Issue

12

Start / End Page

e202200215

Related Subject Headings

  • General Chemistry
  • Catalysis
  • Amines
  • Amination
  • Alkenes
  • 34 Chemical sciences
  • 03 Chemical Sciences