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Trends in HF Hospitalizations Among Young Adults in the United States From 2004 to 2018.

Publication ,  Journal Article
Jain, V; Minhas, AMK; Khan, SU; Greene, SJ; Pandey, A; Van Spall, HGC; Fonarow, GC; Mentz, RJ; Butler, J; Khan, MS
Published in: JACC Heart Fail
May 2022

OBJECTIVES: The aim of this study was to assess trends in heart failure (HF) hospitalizations among young adults. BACKGROUND: Data are limited regarding clinical characteristics and outcomes of young adults hospitalized for HF. METHODS: The National Inpatient Sample database was analyzed to identify adults aged 18 to 45 years who were hospitalized for HF between 2004 and 2018. RESULTS: In total, 767,180 weighted hospitalizations for HF in young adults were identified, equivalent to 4.32 (95% CI: 4.31-4.33) per 10,000 person-years. Overall HF hospitalizations per 10,000 U.S. population of young adults decreased from 2.43 in 2004 to 1.82 in 2012, followed by an increase to 2.51 in 2018. Black adults (50.1%) had a significantly higher proportion of HF hospitalizations compared with White (31.9%) and Hispanic adults (12.2%) throughout the study period. Nearly half of patients (45.8%) lived in zip codes in the lowest quartile of national household income. Overall, in-hospital mortality was 1.3%, which decreased over time; this trend was consistent by sex and race. The overall mean LOS (5.2 days) remained stable over time, while the mean inflation-adjusted cost increased from $12,449 in 2004 to $16,786 in 2018, with significant overall differences by race and sex. CONCLUSIONS: This longitudinal examination of U.S. clinical practice revealed that HF hospitalizations among young adults have increased since 2013. Approximately half of these patients are Black and reside in zip codes in the lowest quartile of national household income. Temporal trends showed decreased in-hospital mortality, stable adjusted lengths of stay, and increased inflation-adjusted costs, with significant racial differences in hospitalization rates.

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Published In

JACC Heart Fail

DOI

EISSN

2213-1787

Publication Date

May 2022

Volume

10

Issue

5

Start / End Page

350 / 362

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Inpatients
  • Humans
  • Hospitalization
  • Hospital Mortality
  • Hispanic or Latino
  • Heart Failure
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

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Jain, V., Minhas, A. M. K., Khan, S. U., Greene, S. J., Pandey, A., Van Spall, H. G. C., … Khan, M. S. (2022). Trends in HF Hospitalizations Among Young Adults in the United States From 2004 to 2018. JACC Heart Fail, 10(5), 350–362. https://doi.org/10.1016/j.jchf.2022.01.021
Jain, Vardhman, Abdul Mannan Khan Minhas, Safi U. Khan, Stephen J. Greene, Ambarish Pandey, Harriette G. C. Van Spall, Gregg C. Fonarow, Robert J. Mentz, Javed Butler, and Muhammad Shahzeb Khan. “Trends in HF Hospitalizations Among Young Adults in the United States From 2004 to 2018.JACC Heart Fail 10, no. 5 (May 2022): 350–62. https://doi.org/10.1016/j.jchf.2022.01.021.
Jain V, Minhas AMK, Khan SU, Greene SJ, Pandey A, Van Spall HGC, et al. Trends in HF Hospitalizations Among Young Adults in the United States From 2004 to 2018. JACC Heart Fail. 2022 May;10(5):350–62.
Jain, Vardhman, et al. “Trends in HF Hospitalizations Among Young Adults in the United States From 2004 to 2018.JACC Heart Fail, vol. 10, no. 5, May 2022, pp. 350–62. Pubmed, doi:10.1016/j.jchf.2022.01.021.
Jain V, Minhas AMK, Khan SU, Greene SJ, Pandey A, Van Spall HGC, Fonarow GC, Mentz RJ, Butler J, Khan MS. Trends in HF Hospitalizations Among Young Adults in the United States From 2004 to 2018. JACC Heart Fail. 2022 May;10(5):350–362.
Journal cover image

Published In

JACC Heart Fail

DOI

EISSN

2213-1787

Publication Date

May 2022

Volume

10

Issue

5

Start / End Page

350 / 362

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Inpatients
  • Humans
  • Hospitalization
  • Hospital Mortality
  • Hispanic or Latino
  • Heart Failure
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology