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Venous Tone and Stressed Blood Volume in Heart Failure: JACC Review Topic of the Week.

Publication ,  Journal Article
Fudim, M; Kaye, DM; Borlaug, BA; Shah, SJ; Rich, S; Kapur, NK; Costanzo, MR; Brener, MI; Sunagawa, K; Burkhoff, D
Published in: J Am Coll Cardiol
May 10, 2022

A number of pathologic processes contribute to the elevation in cardiac filling pressures in heart failure (HF), including myocardial dysfunction and primary volume overload. In this review, we discuss the important role of the venous system and the concepts of stressed blood volume and unstressed blood volume. We review how regulation of venous tone modifies the distribution of blood between these 2 functional compartments, the physical distribution of blood between the pulmonary and systemic circulations, and how these relate to the hemodynamic abnormalities observed in HF. Finally, we review recently applied methods for estimating stressed blood volume and how they are being applied to the results of clinical studies to provide new insights into resting and exercise hemodynamics and therapeutics for HF.

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Published In

J Am Coll Cardiol

DOI

EISSN

1558-3597

Publication Date

May 10, 2022

Volume

79

Issue

18

Start / End Page

1858 / 1869

Location

United States

Related Subject Headings

  • Humans
  • Hemodynamics
  • Heart Failure
  • Cardiovascular System & Hematology
  • Blood Volume
  • 3201 Cardiovascular medicine and haematology
  • 1117 Public Health and Health Services
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Fudim, M., Kaye, D. M., Borlaug, B. A., Shah, S. J., Rich, S., Kapur, N. K., … Burkhoff, D. (2022). Venous Tone and Stressed Blood Volume in Heart Failure: JACC Review Topic of the Week. J Am Coll Cardiol, 79(18), 1858–1869. https://doi.org/10.1016/j.jacc.2022.02.050
Fudim, Marat, David M. Kaye, Barry A. Borlaug, Sanjiv J. Shah, Stuart Rich, Navin K. Kapur, Maria Rosa Costanzo, Michael I. Brener, Kenji Sunagawa, and Daniel Burkhoff. “Venous Tone and Stressed Blood Volume in Heart Failure: JACC Review Topic of the Week.J Am Coll Cardiol 79, no. 18 (May 10, 2022): 1858–69. https://doi.org/10.1016/j.jacc.2022.02.050.
Fudim M, Kaye DM, Borlaug BA, Shah SJ, Rich S, Kapur NK, et al. Venous Tone and Stressed Blood Volume in Heart Failure: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 May 10;79(18):1858–69.
Fudim, Marat, et al. “Venous Tone and Stressed Blood Volume in Heart Failure: JACC Review Topic of the Week.J Am Coll Cardiol, vol. 79, no. 18, May 2022, pp. 1858–69. Pubmed, doi:10.1016/j.jacc.2022.02.050.
Fudim M, Kaye DM, Borlaug BA, Shah SJ, Rich S, Kapur NK, Costanzo MR, Brener MI, Sunagawa K, Burkhoff D. Venous Tone and Stressed Blood Volume in Heart Failure: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 May 10;79(18):1858–1869.
Journal cover image

Published In

J Am Coll Cardiol

DOI

EISSN

1558-3597

Publication Date

May 10, 2022

Volume

79

Issue

18

Start / End Page

1858 / 1869

Location

United States

Related Subject Headings

  • Humans
  • Hemodynamics
  • Heart Failure
  • Cardiovascular System & Hematology
  • Blood Volume
  • 3201 Cardiovascular medicine and haematology
  • 1117 Public Health and Health Services
  • 1102 Cardiorespiratory Medicine and Haematology