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The hypereosinophilic syndrome - an unusual cause of myocarditis and cardioembolic strokes.

Publication ,  Journal Article
Ryan, D; Inamullah, O; El Husseini, N; Wang, E; Selim, MA; Feng, W
Published in: Am J Med Sci
November 2022

Hypereosinophilic syndrome is a rare disorder characterized by excessive peripheral eosinophilia and eosinophil associated end-organ damage. Clinical presentations are heterogenous and can involve skin, pulmonary, cardiac and neurologic dysfunction. Eosinophilic myocarditis is a life-threatening complication that increases the risk of cardiac microemboli, which can subsequently lead to embolic strokes. Secondary to changes in blood viscosity, impaired clearance of microemboli, impaired cerebral blood flow, and pro-thrombotic conditions in the setting of hypereosinophilia, infarcts often present in vascular border zone regions. Here we present two cases of cardioembolic strokes involving borderzone regions in the setting of hypereosinophilic syndrome.

Duke Scholars

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Published In

Am J Med Sci

DOI

EISSN

1538-2990

Publication Date

November 2022

Volume

364

Issue

5

Start / End Page

661 / 668

Location

United States

Related Subject Headings

  • Myocarditis
  • Hypereosinophilic Syndrome
  • Humans
  • General & Internal Medicine
  • Eosinophils
  • Embolic Stroke
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences
 

Citation

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Ryan, D., Inamullah, O., El Husseini, N., Wang, E., Selim, M. A., & Feng, W. (2022). The hypereosinophilic syndrome - an unusual cause of myocarditis and cardioembolic strokes. Am J Med Sci, 364(5), 661–668. https://doi.org/10.1016/j.amjms.2022.05.019
Ryan, Dylan, Ovais Inamullah, Nada El Husseini, Endi Wang, M Angelica Selim, and Wuwei Feng. “The hypereosinophilic syndrome - an unusual cause of myocarditis and cardioembolic strokes.Am J Med Sci 364, no. 5 (November 2022): 661–68. https://doi.org/10.1016/j.amjms.2022.05.019.
Ryan D, Inamullah O, El Husseini N, Wang E, Selim MA, Feng W. The hypereosinophilic syndrome - an unusual cause of myocarditis and cardioembolic strokes. Am J Med Sci. 2022 Nov;364(5):661–8.
Ryan, Dylan, et al. “The hypereosinophilic syndrome - an unusual cause of myocarditis and cardioembolic strokes.Am J Med Sci, vol. 364, no. 5, Nov. 2022, pp. 661–68. Pubmed, doi:10.1016/j.amjms.2022.05.019.
Ryan D, Inamullah O, El Husseini N, Wang E, Selim MA, Feng W. The hypereosinophilic syndrome - an unusual cause of myocarditis and cardioembolic strokes. Am J Med Sci. 2022 Nov;364(5):661–668.
Journal cover image

Published In

Am J Med Sci

DOI

EISSN

1538-2990

Publication Date

November 2022

Volume

364

Issue

5

Start / End Page

661 / 668

Location

United States

Related Subject Headings

  • Myocarditis
  • Hypereosinophilic Syndrome
  • Humans
  • General & Internal Medicine
  • Eosinophils
  • Embolic Stroke
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences