Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial.
Publication
, Journal Article
Vogel, RF; Delewi, R; Wilschut, JM; Lemmert, ME; Diletti, R; van Vliet, R; van der Waarden, NWPL; Nuis, R-J; Paradies, V; Alexopoulos, D ...
Published in: Am Heart J
October 2022
The present research letter reports the 1-year clinical outcomes of the randomized COMPARE CRUSH trial, which allocated STEMI patients at first medical contact in the ambulance to receive either crushed or integral tablets of prasugrel loading dose. This trial aimed to investigate whether early enhanced antiplatelet effect constituted by the crushed potent oral P2Y12 inhibitor prasugrel could lead to improved early myocardial reperfusion and clinical outcomes.
Duke Scholars
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Published In
Am Heart J
DOI
EISSN
1097-6744
Publication Date
October 2022
Volume
252
Start / End Page
26 / 30
Location
United States
Related Subject Headings
- Treatment Outcome
- Tablets
- ST Elevation Myocardial Infarction
- Purinergic P2Y Receptor Antagonists
- Prasugrel Hydrochloride
- Platelet Aggregation Inhibitors
- Percutaneous Coronary Intervention
- Humans
- Follow-Up Studies
- Emergency Medical Services
Citation
APA
Chicago
ICMJE
MLA
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Vogel, R. F., Delewi, R., Wilschut, J. M., Lemmert, M. E., Diletti, R., van Vliet, R., … Vlachojannis, G. J. (2022). Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial. Am Heart J, 252, 26–30. https://doi.org/10.1016/j.ahj.2022.05.022
Vogel, Rosanne F., Ronak Delewi, Jeroen M. Wilschut, Miguel E. Lemmert, Roberto Diletti, Ria van Vliet, Nancy W. P. L. van der Waarden, et al. “Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial.” Am Heart J 252 (October 2022): 26–30. https://doi.org/10.1016/j.ahj.2022.05.022.
Vogel RF, Delewi R, Wilschut JM, Lemmert ME, Diletti R, van Vliet R, et al. Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial. Am Heart J. 2022 Oct;252:26–30.
Vogel, Rosanne F., et al. “Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial.” Am Heart J, vol. 252, Oct. 2022, pp. 26–30. Pubmed, doi:10.1016/j.ahj.2022.05.022.
Vogel RF, Delewi R, Wilschut JM, Lemmert ME, Diletti R, van Vliet R, van der Waarden NWPL, Nuis R-J, Paradies V, Alexopoulos D, Zijlstra F, Montalescot G, Angiolillo DJ, Krucoff MW, Smits PC, Van Mieghem NM, Vlachojannis GJ. Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial. Am Heart J. 2022 Oct;252:26–30.
Published In
Am Heart J
DOI
EISSN
1097-6744
Publication Date
October 2022
Volume
252
Start / End Page
26 / 30
Location
United States
Related Subject Headings
- Treatment Outcome
- Tablets
- ST Elevation Myocardial Infarction
- Purinergic P2Y Receptor Antagonists
- Prasugrel Hydrochloride
- Platelet Aggregation Inhibitors
- Percutaneous Coronary Intervention
- Humans
- Follow-Up Studies
- Emergency Medical Services