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Characterising the long-term clinical outcomes of 1190 hospitalised patients with COVID-19 in New York City: a retrospective case series.

Publication ,  Journal Article
Shoucri, SM; Purpura, L; DeLaurentis, C; Adan, MA; Theodore, DA; Irace, AL; Robbins-Juarez, SY; Khedagi, AM; Letchford, D; Harb, AA; Lee, KE ...
Published in: BMJ open
June 2021

To characterise the long-term outcomes of patients with COVID-19 admitted to a large New York City medical centre at 3 and 6 months after hospitalisation and describe their healthcare usage, symptoms, morbidity and mortality.Retrospective cohort through manual chart review of the electronic medical record.NewYork-Presbyterian/Columbia University Irving Medical Center, a quaternary care academic medical centre in New York City.The first 1190 consecutive patients with symptoms of COVID-19 who presented to the hospital for care between 1 March and 8 April 2020 and tested positive for SARS-CoV-2 on reverse transcriptase PCR assay.Type and frequency of follow-up encounters, self-reported symptoms, morbidity and mortality at 3 and 6 months after presentation, respectively; patient disposition information prior to admission, at discharge, and at 3 and 6 months after hospital presentation.Of the 1190 reviewed patients, 929 survived their initial hospitalisation and 261 died. Among survivors, 570 had follow-up encounters (488 at 3 months and 364 at 6 months). An additional 33 patients died in the follow-up period. In the first 3 months after admission, most encounters were telehealth visits (59%). Cardiopulmonary symptoms (35.7% and 28%), especially dyspnoea (22.1% and 15.9%), were the most common reported symptoms at 3-month and 6-month encounters, respectively. Additionally, a large number of patients reported generalised (26.4%) or neuropsychiatric (24.2%) symptoms 6 months after hospitalisation. Patients with severe COVID-19 were more likely to have reduced mobility, reduced independence or a new dialysis requirement in the 6 months after hospitalisation.Patients hospitalised with SARS-CoV-2 infection reported persistent symptoms up to 6 months after diagnosis. These results highlight the long-term morbidity of COVID-19 and its burden on patients and healthcare resources.

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Published In

BMJ open

DOI

EISSN

2044-6055

ISSN

2044-6055

Publication Date

June 2021

Volume

11

Issue

6

Start / End Page

e049488

Related Subject Headings

  • SARS-CoV-2
  • Retrospective Studies
  • New York City
  • Humans
  • Hospitalization
  • COVID-19
  • 52 Psychology
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 1199 Other Medical and Health Sciences
 

Citation

APA
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Shoucri, S. M., Purpura, L., DeLaurentis, C., Adan, M. A., Theodore, D. A., Irace, A. L., … Zucker, J. E. (2021). Characterising the long-term clinical outcomes of 1190 hospitalised patients with COVID-19 in New York City: a retrospective case series. BMJ Open, 11(6), e049488. https://doi.org/10.1136/bmjopen-2021-049488
Shoucri, Sherif M., Lawrence Purpura, Clare DeLaurentis, Matthew A. Adan, Deborah A. Theodore, Alexandria Lauren Irace, Shelief Y. Robbins-Juarez, et al. “Characterising the long-term clinical outcomes of 1190 hospitalised patients with COVID-19 in New York City: a retrospective case series.BMJ Open 11, no. 6 (June 2021): e049488. https://doi.org/10.1136/bmjopen-2021-049488.
Shoucri SM, Purpura L, DeLaurentis C, Adan MA, Theodore DA, Irace AL, et al. Characterising the long-term clinical outcomes of 1190 hospitalised patients with COVID-19 in New York City: a retrospective case series. BMJ open. 2021 Jun;11(6):e049488.
Shoucri, Sherif M., et al. “Characterising the long-term clinical outcomes of 1190 hospitalised patients with COVID-19 in New York City: a retrospective case series.BMJ Open, vol. 11, no. 6, June 2021, p. e049488. Epmc, doi:10.1136/bmjopen-2021-049488.
Shoucri SM, Purpura L, DeLaurentis C, Adan MA, Theodore DA, Irace AL, Robbins-Juarez SY, Khedagi AM, Letchford D, Harb AA, Zerihun LM, Lee KE, Gambina K, Lauring MC, Chen N, Sperring CP, Mehta SS, Myers EL, Shih H, Argenziano MG, Bruce SL, Slater CL, Tiao JR, Natarajan K, Hripcsak G, Chen R, Yin MT, Sobieszczyk ME, Castor D, Zucker JE. Characterising the long-term clinical outcomes of 1190 hospitalised patients with COVID-19 in New York City: a retrospective case series. BMJ open. 2021 Jun;11(6):e049488.

Published In

BMJ open

DOI

EISSN

2044-6055

ISSN

2044-6055

Publication Date

June 2021

Volume

11

Issue

6

Start / End Page

e049488

Related Subject Headings

  • SARS-CoV-2
  • Retrospective Studies
  • New York City
  • Humans
  • Hospitalization
  • COVID-19
  • 52 Psychology
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 1199 Other Medical and Health Sciences