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Comparison of the association of masked hypertension defined by the 2017 ACC/AHA BP guideline versus the JNC7 guideline with left ventricular hypertrophy.

Publication ,  Journal Article
Poudel, B; Viera, AJ; Shimbo, D; Schwartz, JE; Shikany, JM; Sakhuja, S; Lloyd-Jones, DM; Muntner, P; Yano, Y
Published in: J Hypertens
August 1, 2022

BACKGROUND: Compared with the Seventh Report of the Joint National Committee (JNC7), the 2017 American College of Cardiology/American Heart Association (ACC/AHA) blood pressure (BP) guideline uses lower BP thresholds to define hypertension and BP control. METHODS: We pooled data from five US-based studies to compare the association of masked hypertension (MHT) and masked uncontrolled hypertension, defined using the 2017 ACC/AHA guideline ( n  = 1653 without high office BP; <130/80 mmHg) versus the JNC7 guideline ( n  = 2451 without high office BP; <140/90 mmHg), with left ventricular hypertrophy (LVH). MHT and masked uncontrolled hypertension were defined using office BP and awake BP alone and awake, asleep, or 24-h BP. LVH was assessed by echocardiography. RESULTS: Among participants without high office BP not taking antihypertensive medication, the prevalence of MHT defined by the JNC7 guideline and the 2017 ACC/AHA BP guideline was 25.0 and 33.5% using awake BP only and 37.1 and 52.0% when using awake, asleep, or 24-h BP. The adjusted prevalence ratios for LVH associated with MHT versus sustained normotension defined by the JNC7 and 2017 ACC/AHA BP guidelines were 1.72 [95% confidence interval (CI): 1.12-2.64] and 1.56 (95% CI: 0.97-2.51), respectively, when using awake BP only and 2.16 (95% CI: 1.36-3.44) and 1.03 (95% CI: 0.58-1.82), respectively, when using awake, asleep or 24-h BP. There was no evidence that masked uncontrolled hypertension was associated with LVH when defined using the BP thresholds in either the JNC7 or the 2017 ACC/AHA BP guideline. CONCLUSION: The association of MHT with LVH may depend on the BP thresholds used.

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Published In

J Hypertens

DOI

EISSN

1473-5598

Publication Date

August 1, 2022

Volume

40

Issue

8

Start / End Page

1597 / 1606

Location

Netherlands

Related Subject Headings

  • United States
  • Prevalence
  • Masked Hypertension
  • Hypertrophy, Left Ventricular
  • Hypertension
  • Humans
  • Cardiovascular System & Hematology
  • Blood Pressure
  • Antihypertensive Agents
  • 3202 Clinical sciences
 

Citation

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Poudel, B., Viera, A. J., Shimbo, D., Schwartz, J. E., Shikany, J. M., Sakhuja, S., … Yano, Y. (2022). Comparison of the association of masked hypertension defined by the 2017 ACC/AHA BP guideline versus the JNC7 guideline with left ventricular hypertrophy. J Hypertens, 40(8), 1597–1606. https://doi.org/10.1097/HJH.0000000000003192
Poudel, Bharat, Anthony J. Viera, Daichi Shimbo, Joseph E. Schwartz, James M. Shikany, Swati Sakhuja, Donald M. Lloyd-Jones, Paul Muntner, and Yuichiro Yano. “Comparison of the association of masked hypertension defined by the 2017 ACC/AHA BP guideline versus the JNC7 guideline with left ventricular hypertrophy.J Hypertens 40, no. 8 (August 1, 2022): 1597–1606. https://doi.org/10.1097/HJH.0000000000003192.
Poudel B, Viera AJ, Shimbo D, Schwartz JE, Shikany JM, Sakhuja S, et al. Comparison of the association of masked hypertension defined by the 2017 ACC/AHA BP guideline versus the JNC7 guideline with left ventricular hypertrophy. J Hypertens. 2022 Aug 1;40(8):1597–606.
Poudel, Bharat, et al. “Comparison of the association of masked hypertension defined by the 2017 ACC/AHA BP guideline versus the JNC7 guideline with left ventricular hypertrophy.J Hypertens, vol. 40, no. 8, Aug. 2022, pp. 1597–606. Pubmed, doi:10.1097/HJH.0000000000003192.
Poudel B, Viera AJ, Shimbo D, Schwartz JE, Shikany JM, Sakhuja S, Lloyd-Jones DM, Muntner P, Yano Y. Comparison of the association of masked hypertension defined by the 2017 ACC/AHA BP guideline versus the JNC7 guideline with left ventricular hypertrophy. J Hypertens. 2022 Aug 1;40(8):1597–1606.

Published In

J Hypertens

DOI

EISSN

1473-5598

Publication Date

August 1, 2022

Volume

40

Issue

8

Start / End Page

1597 / 1606

Location

Netherlands

Related Subject Headings

  • United States
  • Prevalence
  • Masked Hypertension
  • Hypertrophy, Left Ventricular
  • Hypertension
  • Humans
  • Cardiovascular System & Hematology
  • Blood Pressure
  • Antihypertensive Agents
  • 3202 Clinical sciences