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Sugammadex-associated asystole in young obese patient: Case report

Publication ,  Journal Article
Lohmeier, SJ; Powers, DB
Published in: Oral and Maxillofacial Surgery Cases
September 1, 2022

Sugammadex is a neuromuscular blocking (NMB) reversal agent that has quickly become popular among anesthesia providers since its FDA approval in 2015 due to its favorable properties. There are rare but significant and increasingly reported adverse cardiac events, including symptomatic bradycardia, asystole, cardiac arrest, and death. Since its introduction into the United States (US) market, there have been ten reported cases of asystole and cardiac arrest within minutes of sugammadex administration. Some incidents required cardiopulmonary resuscitation (CPR) and prolonged treatment in the Intensive Care Unit (ICU) for successful management. We present the youngest known case of sugammadex-associated asystole in a non-cardiac patient. Further investigation is warranted to understand better both the patient-related factors and drug administration techniques involved in Sugammadex-associated cardiovascular compromise to improve clinical decision-making for anesthesia providers.

Duke Scholars

Published In

Oral and Maxillofacial Surgery Cases

DOI

EISSN

2214-5419

Publication Date

September 1, 2022

Volume

8

Issue

3
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lohmeier, S. J., & Powers, D. B. (2022). Sugammadex-associated asystole in young obese patient: Case report. Oral and Maxillofacial Surgery Cases, 8(3). https://doi.org/10.1016/j.omsc.2022.100271
Lohmeier, S. J., and D. B. Powers. “Sugammadex-associated asystole in young obese patient: Case report.” Oral and Maxillofacial Surgery Cases 8, no. 3 (September 1, 2022). https://doi.org/10.1016/j.omsc.2022.100271.
Lohmeier SJ, Powers DB. Sugammadex-associated asystole in young obese patient: Case report. Oral and Maxillofacial Surgery Cases. 2022 Sep 1;8(3).
Lohmeier, S. J., and D. B. Powers. “Sugammadex-associated asystole in young obese patient: Case report.” Oral and Maxillofacial Surgery Cases, vol. 8, no. 3, Sept. 2022. Scopus, doi:10.1016/j.omsc.2022.100271.
Lohmeier SJ, Powers DB. Sugammadex-associated asystole in young obese patient: Case report. Oral and Maxillofacial Surgery Cases. 2022 Sep 1;8(3).
Journal cover image

Published In

Oral and Maxillofacial Surgery Cases

DOI

EISSN

2214-5419

Publication Date

September 1, 2022

Volume

8

Issue

3