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Can viruses help us to understand and classify the MHC class I molecules at the maternal-fetal interface?

Publication ,  Conference
Furman, MH; Ploegh, HL; Schust, DJ
Published in: Hum Immunol
November 2000

Placental expression of HLA-C, HLA-E, and HLA-G locus products is now well described. However, to date, the functional relevance of these MHC class I products at the maternal-fetal interface is incompletely described. We propose here that HLA-C, -E, and -G comprise a distinct and cohesive group of MHC class I products. This hypothesis is supported by a growing body of data, including that obtained through the study of viral immune evasion. Continued investigation of viral interactions with MHC class I products promises to help us to define those specific attributes of HLA-C, -E, and -G that define their common characteristics.

Duke Scholars

Published In

Hum Immunol

DOI

ISSN

0198-8859

Publication Date

November 2000

Volume

61

Issue

11

Start / End Page

1169 / 1176

Location

United States

Related Subject Headings

  • Virus Diseases
  • Placenta
  • Killer Cells, Natural
  • Immunology
  • Immunity, Cellular
  • Humans
  • Histocompatibility Antigens Class I
  • Cytomegalovirus
  • 1107 Immunology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Furman, M. H., Ploegh, H. L., & Schust, D. J. (2000). Can viruses help us to understand and classify the MHC class I molecules at the maternal-fetal interface? In Hum Immunol (Vol. 61, pp. 1169–1176). United States. https://doi.org/10.1016/s0198-8859(00)00203-2
Furman, M. H., H. L. Ploegh, and D. J. Schust. “Can viruses help us to understand and classify the MHC class I molecules at the maternal-fetal interface?” In Hum Immunol, 61:1169–76, 2000. https://doi.org/10.1016/s0198-8859(00)00203-2.
Furman MH, Ploegh HL, Schust DJ. Can viruses help us to understand and classify the MHC class I molecules at the maternal-fetal interface? In: Hum Immunol. 2000. p. 1169–76.
Furman, M. H., et al. “Can viruses help us to understand and classify the MHC class I molecules at the maternal-fetal interface?Hum Immunol, vol. 61, no. 11, 2000, pp. 1169–76. Pubmed, doi:10.1016/s0198-8859(00)00203-2.
Journal cover image

Published In

Hum Immunol

DOI

ISSN

0198-8859

Publication Date

November 2000

Volume

61

Issue

11

Start / End Page

1169 / 1176

Location

United States

Related Subject Headings

  • Virus Diseases
  • Placenta
  • Killer Cells, Natural
  • Immunology
  • Immunity, Cellular
  • Humans
  • Histocompatibility Antigens Class I
  • Cytomegalovirus
  • 1107 Immunology