Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke.
Publication
, Journal Article
Videen, TO; Zazulia, AR; Manno, EM; Derdeyn, CP; Adams, RE; Diringer, MN; Powers, WJ
Published in: Neurology
December 11, 2001
Changes in brain tissue volume in six patients who had acute complete middle cerebral artery (MCA) infarctions and CT evidence of midline shift were measured using the brain boundary shift integral (BBSI) on sequential T1-weighted MR images acquired before and after a 1.5-g/kg bolus infusion of mannitol. At 50 to 55 minutes after the baseline scan, total brain volume decreased by 8.1 +/- 2.8 mL (0.6%, p < 0.005). Brain in the noninfarcted hemisphere shrank more (0.8 +/- 0.4%) than in the infarcted hemisphere (0.0 +/- 0.5%, p < 0.05).
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Published In
Neurology
DOI
ISSN
0028-3878
Publication Date
December 11, 2001
Volume
57
Issue
11
Start / End Page
2120 / 2122
Location
United States
Related Subject Headings
- Tomography, X-Ray Computed
- Neurology & Neurosurgery
- Middle Aged
- Mannitol
- Male
- Magnetic Resonance Imaging
- Infusions, Intravenous
- Infarction, Middle Cerebral Artery
- Humans
- Female
Citation
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MLA
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Videen, T. O., Zazulia, A. R., Manno, E. M., Derdeyn, C. P., Adams, R. E., Diringer, M. N., & Powers, W. J. (2001). Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke. Neurology, 57(11), 2120–2122. https://doi.org/10.1212/wnl.57.11.2120
Videen, T. O., A. R. Zazulia, E. M. Manno, C. P. Derdeyn, R. E. Adams, M. N. Diringer, and W. J. Powers. “Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke.” Neurology 57, no. 11 (December 11, 2001): 2120–22. https://doi.org/10.1212/wnl.57.11.2120.
Videen TO, Zazulia AR, Manno EM, Derdeyn CP, Adams RE, Diringer MN, et al. Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke. Neurology. 2001 Dec 11;57(11):2120–2.
Videen, T. O., et al. “Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke.” Neurology, vol. 57, no. 11, Dec. 2001, pp. 2120–22. Pubmed, doi:10.1212/wnl.57.11.2120.
Videen TO, Zazulia AR, Manno EM, Derdeyn CP, Adams RE, Diringer MN, Powers WJ. Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke. Neurology. 2001 Dec 11;57(11):2120–2122.
Published In
Neurology
DOI
ISSN
0028-3878
Publication Date
December 11, 2001
Volume
57
Issue
11
Start / End Page
2120 / 2122
Location
United States
Related Subject Headings
- Tomography, X-Ray Computed
- Neurology & Neurosurgery
- Middle Aged
- Mannitol
- Male
- Magnetic Resonance Imaging
- Infusions, Intravenous
- Infarction, Middle Cerebral Artery
- Humans
- Female