The Impact of Landscape Changes on Data and Safety Monitoring Board Oversight of Clinical Trials.
Publication
, Journal Article
Abebe, KZ; Rockhold, FW
Published in: NEJM Evid
September 2022
Impact of Landscape Changes on DSMB OversightThis Clinical Trials Workshop describes how external factors (or landscape changes) can affect monitoring of an ongoing clinical trial and discusses issues to consider to avoid stopping a trial too early while maintaining equipoise for enrolled participants. Three clinical trials in which DSMBs had to consider the effects of landscape changes on the continued performance of the monitored trial are reviewed.
Duke Scholars
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Published In
NEJM Evid
DOI
EISSN
2766-5526
Publication Date
September 2022
Volume
1
Issue
9
Start / End Page
EVIDctw2100019
Location
United States
Related Subject Headings
- Humans
- Clinical Trials Data Monitoring Committees
Citation
APA
Chicago
ICMJE
MLA
NLM
Abebe, K. Z., & Rockhold, F. W. (2022). The Impact of Landscape Changes on Data and Safety Monitoring Board Oversight of Clinical Trials. NEJM Evid, 1(9), EVIDctw2100019. https://doi.org/10.1056/EVIDctw2100019
Abebe, Kaleab Z., and Frank W. Rockhold. “The Impact of Landscape Changes on Data and Safety Monitoring Board Oversight of Clinical Trials.” NEJM Evid 1, no. 9 (September 2022): EVIDctw2100019. https://doi.org/10.1056/EVIDctw2100019.
Abebe KZ, Rockhold FW. The Impact of Landscape Changes on Data and Safety Monitoring Board Oversight of Clinical Trials. NEJM Evid. 2022 Sep;1(9):EVIDctw2100019.
Abebe, Kaleab Z., and Frank W. Rockhold. “The Impact of Landscape Changes on Data and Safety Monitoring Board Oversight of Clinical Trials.” NEJM Evid, vol. 1, no. 9, Sept. 2022, p. EVIDctw2100019. Pubmed, doi:10.1056/EVIDctw2100019.
Abebe KZ, Rockhold FW. The Impact of Landscape Changes on Data and Safety Monitoring Board Oversight of Clinical Trials. NEJM Evid. 2022 Sep;1(9):EVIDctw2100019.
Published In
NEJM Evid
DOI
EISSN
2766-5526
Publication Date
September 2022
Volume
1
Issue
9
Start / End Page
EVIDctw2100019
Location
United States
Related Subject Headings
- Humans
- Clinical Trials Data Monitoring Committees