Skip to main content

Cutaneous Squamous Cell Carcinoma Arising in Immunosuppressed Patients: A Systematic Review of Tumor Profiling Studies.

Publication ,  Journal Article
Blue, ED; Freeman, SC; Lobl, MB; Clarey, DD; Fredrick, RL; Wysong, A; Whitley, MJ
Published in: JID Innov
July 2022

As solid organ transplantation becomes more prevalent, more individuals are living as members of the immunosuppressed population with an elevated risk for cutaneous squamous cell carcinoma (cSCC). Although great progress has been made in understanding the pathogenesis of cSCC in general, little is known about the drivers of tumorigenesis in immunosuppressed patients and organ-transplant recipients, specifically. This systematic review sought to synthesize information regarding the genetic and epigenetic alterations as well as changes in protein and mRNA expression that place this growing population at risk for cSCC, influence treatment response, and promote tumor aggressiveness. This review will provide investigators with a framework to identify future areas of investigation and clinicians with additional insight into how to best manage these patients.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

JID Innov

DOI

EISSN

2667-0267

Publication Date

July 2022

Volume

2

Issue

4

Start / End Page

100126

Location

Netherlands
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Blue, E. D., Freeman, S. C., Lobl, M. B., Clarey, D. D., Fredrick, R. L., Wysong, A., & Whitley, M. J. (2022). Cutaneous Squamous Cell Carcinoma Arising in Immunosuppressed Patients: A Systematic Review of Tumor Profiling Studies. JID Innov, 2(4), 100126. https://doi.org/10.1016/j.xjidi.2022.100126
Blue, Elliot D., S Caleb Freeman, Marissa B. Lobl, Dillon D. Clarey, Rose L. Fredrick, Ashley Wysong, and Melodi Javid Whitley. “Cutaneous Squamous Cell Carcinoma Arising in Immunosuppressed Patients: A Systematic Review of Tumor Profiling Studies.JID Innov 2, no. 4 (July 2022): 100126. https://doi.org/10.1016/j.xjidi.2022.100126.
Blue ED, Freeman SC, Lobl MB, Clarey DD, Fredrick RL, Wysong A, et al. Cutaneous Squamous Cell Carcinoma Arising in Immunosuppressed Patients: A Systematic Review of Tumor Profiling Studies. JID Innov. 2022 Jul;2(4):100126.
Blue, Elliot D., et al. “Cutaneous Squamous Cell Carcinoma Arising in Immunosuppressed Patients: A Systematic Review of Tumor Profiling Studies.JID Innov, vol. 2, no. 4, July 2022, p. 100126. Pubmed, doi:10.1016/j.xjidi.2022.100126.
Blue ED, Freeman SC, Lobl MB, Clarey DD, Fredrick RL, Wysong A, Whitley MJ. Cutaneous Squamous Cell Carcinoma Arising in Immunosuppressed Patients: A Systematic Review of Tumor Profiling Studies. JID Innov. 2022 Jul;2(4):100126.

Published In

JID Innov

DOI

EISSN

2667-0267

Publication Date

July 2022

Volume

2

Issue

4

Start / End Page

100126

Location

Netherlands