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Identifying the trigger of c-IAPs: structural and functional characterization of CARD-mediated modulation of ubiquitin ligase activity.

Publication ,  Journal Article
Oetjen, KA; Duckett, CS
Published in: Mol Cell
June 10, 2011

In this issue of Molecular Cell, Lopez et al. (2011) examine the caspase-recruitment domain (CARD) of c-IAP1 to reveal an intriguing mechanism in which conformational changes of the CARD determine c-IAP1's ubiquitin ligase activity, with implications for regulation of cell proliferation and survival by the IAPs.

Duke Scholars

Published In

Mol Cell

DOI

EISSN

1097-4164

Publication Date

June 10, 2011

Volume

42

Issue

5

Start / End Page

553 / 554

Location

United States

Related Subject Headings

  • Developmental Biology
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

Citation

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MLA
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Oetjen, K. A., & Duckett, C. S. (2011). Identifying the trigger of c-IAPs: structural and functional characterization of CARD-mediated modulation of ubiquitin ligase activity. Mol Cell, 42(5), 553–554. https://doi.org/10.1016/j.molcel.2011.05.018
Oetjen, Karolyn A., and Colin S. Duckett. “Identifying the trigger of c-IAPs: structural and functional characterization of CARD-mediated modulation of ubiquitin ligase activity.Mol Cell 42, no. 5 (June 10, 2011): 553–54. https://doi.org/10.1016/j.molcel.2011.05.018.
Oetjen, Karolyn A., and Colin S. Duckett. “Identifying the trigger of c-IAPs: structural and functional characterization of CARD-mediated modulation of ubiquitin ligase activity.Mol Cell, vol. 42, no. 5, June 2011, pp. 553–54. Pubmed, doi:10.1016/j.molcel.2011.05.018.
Journal cover image

Published In

Mol Cell

DOI

EISSN

1097-4164

Publication Date

June 10, 2011

Volume

42

Issue

5

Start / End Page

553 / 554

Location

United States

Related Subject Headings

  • Developmental Biology
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences
  • 06 Biological Sciences