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Stiehm's Immune Deficiencies: Inborn Errors of Immunity

Cultured thymus tissue transplantation

Publication ,  Chapter
Markert, ML; McCarthy, EA; Gupton, SE; Lim, AP
January 1, 2020

Transplantation of thymic tissue was initially attempted in the 1960s and 1970s. Long-term successes were rare but these studies served as an important foundation. Today, cultured thymus tissue transplantation (CTTT) is performed for athymic infants. Almost all CTTT recipients are infants with complete DiGeorge anomaly. CTTT is an investigational product regulated by the FDA. Duke is only center in the United States performing thymus transplantation and this chapter reviews the experience to date.

Duke Scholars

DOI

ISBN

9780128172957

Publication Date

January 1, 2020

Start / End Page

1229 / 1240
 

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Markert, M. L., McCarthy, E. A., Gupton, S. E., & Lim, A. P. (2020). Cultured thymus tissue transplantation. In Stiehm’s Immune Deficiencies: Inborn Errors of Immunity (pp. 1229–1240). https://doi.org/10.1016/B978-0-12-816768-7.00059-4
Markert, M. L., E. A. McCarthy, S. E. Gupton, and A. P. Lim. “Cultured thymus tissue transplantation.” In Stiehm’s Immune Deficiencies: Inborn Errors of Immunity, 1229–40, 2020. https://doi.org/10.1016/B978-0-12-816768-7.00059-4.
Markert ML, McCarthy EA, Gupton SE, Lim AP. Cultured thymus tissue transplantation. In: Stiehm’s Immune Deficiencies: Inborn Errors of Immunity. 2020. p. 1229–40.
Markert, M. L., et al. “Cultured thymus tissue transplantation.” Stiehm’s Immune Deficiencies: Inborn Errors of Immunity, 2020, pp. 1229–40. Scopus, doi:10.1016/B978-0-12-816768-7.00059-4.
Markert ML, McCarthy EA, Gupton SE, Lim AP. Cultured thymus tissue transplantation. Stiehm’s Immune Deficiencies: Inborn Errors of Immunity. 2020. p. 1229–1240.
Journal cover image

DOI

ISBN

9780128172957

Publication Date

January 1, 2020

Start / End Page

1229 / 1240