Continuous Monitoring of Heart Rate Variability and Clinical Outcomes in Patients with Implantable Cardioverter Defibrillators.
While heart rate variability (HRV) is an established marker of cardiovascular health, the extent to which continuously measured HRV changes over time and the relationship between these changes and clinical outcomes are less clear. We performed a health system analysis of 225 patients implanted with a cardiac defibrillator or cardiac resynchronization device (CRT) with continuous HRV recording capabilities. We found that continuously measured HRV changed modestly over 2 years. Low baseline HRV, which is associated with low parasympathetic tone and/or increases in sympathetic tone, pertains a worse clinical prognosis as reflected by a significant association with all-cause hospitalization. Observed changes in HRV over 6-months of follow-up were not associated with subsequent outcomes.
Duke Scholars
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Related Subject Headings
- Treatment Outcome
- Prognosis
- Humans
- Heart Rate
- Heart Failure
- Defibrillators, Implantable
- Cardiovascular System & Hematology
- Cardiac Resynchronization Therapy
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Treatment Outcome
- Prognosis
- Humans
- Heart Rate
- Heart Failure
- Defibrillators, Implantable
- Cardiovascular System & Hematology
- Cardiac Resynchronization Therapy
- 3201 Cardiovascular medicine and haematology
- 1102 Cardiorespiratory Medicine and Haematology