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Resuscitation in hip fractures: a systematic review.

Publication ,  Journal Article
Rocos, B; Whitehouse, MR; Kelly, MB
Published in: BMJ Open
May 4, 2017

UNLABELLED: To evaluate the evidence for the resuscitation of patients with hip fracture in the preoperative or perioperative phase of their treatment and its impact on mortality. DESIGN: We searched MEDLINE, EMBASE, CENTRAL and PROSPERO databases using a systematic search strategy for randomised trials and observational studies investigating the fluid resuscitation of any patient with hip fracture. No language limits were applied to the search, which was complemented by manually screening the reference lists of appropriate studies. OUTCOME MEASURES: Mortality at 1 week, 30 days and 1 year following surgery. RESULTS: Two hundred and ninety-eight citations were identified, and 12 full manuscripts were reviewed; no studies satisfied the inclusion criteria. The background literature showed that the mortality for these patients at 30 days is approximately 8.5% and that bone cement implantation syndrome is insufficient to explain this. The literature was explored to define the need for an interventional investigation into the preoperative resuscitation of patients with hip fracture. CONCLUSIONS: Patients with hip fracture show similar physiological disturbance to major trauma patients. Nineteen per cent of patients presenting with hip fracture are hypoperfused and 50% show preoperative anaemia suggesting that under resuscitation is a common problem that has not been investigated. A properly conducted interventional trial could improve the outcome of these vulnerable patients.

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Published In

BMJ Open

DOI

EISSN

2044-6055

Publication Date

May 4, 2017

Volume

7

Issue

4

Start / End Page

e015906

Location

England

Related Subject Headings

  • Resuscitation
  • Postoperative Complications
  • Humans
  • Hip Fractures
  • Evidence-Based Medicine
  • England
  • Comorbidity
  • Biomedical Research
  • Anemia
  • Age Factors
 

Citation

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Rocos, B., Whitehouse, M. R., & Kelly, M. B. (2017). Resuscitation in hip fractures: a systematic review. BMJ Open, 7(4), e015906. https://doi.org/10.1136/bmjopen-2017-015906
Rocos, Brett, Michael R. Whitehouse, and Michael B. Kelly. “Resuscitation in hip fractures: a systematic review.BMJ Open 7, no. 4 (May 4, 2017): e015906. https://doi.org/10.1136/bmjopen-2017-015906.
Rocos B, Whitehouse MR, Kelly MB. Resuscitation in hip fractures: a systematic review. BMJ Open. 2017 May 4;7(4):e015906.
Rocos, Brett, et al. “Resuscitation in hip fractures: a systematic review.BMJ Open, vol. 7, no. 4, May 2017, p. e015906. Pubmed, doi:10.1136/bmjopen-2017-015906.
Rocos B, Whitehouse MR, Kelly MB. Resuscitation in hip fractures: a systematic review. BMJ Open. 2017 May 4;7(4):e015906.

Published In

BMJ Open

DOI

EISSN

2044-6055

Publication Date

May 4, 2017

Volume

7

Issue

4

Start / End Page

e015906

Location

England

Related Subject Headings

  • Resuscitation
  • Postoperative Complications
  • Humans
  • Hip Fractures
  • Evidence-Based Medicine
  • England
  • Comorbidity
  • Biomedical Research
  • Anemia
  • Age Factors