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Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Report and Review of the Literature.

Publication ,  Journal Article
Hinson, ARP; Patel, N; Kaplan, J
Published in: J Pediatr Hematol Oncol
January 2021

A toddler undergoing treatment for refractory Langerhans cell histiocytosis (LCH) developed concurrent hemophagocytic lymphohistiocytosis (HLH). These are thought to be distinct histiocytic disorders, with different pathophysiologies, diagnostic criteria, and treatments. HLH in a patient with LCH is thought to be quite rare. In this report, we review the presentation of our patient, as well as review the existing literature of other pediatric patients who have been diagnosed with both LCH and HLH.

Duke Scholars

Published In

J Pediatr Hematol Oncol

DOI

EISSN

1536-3678

Publication Date

January 2021

Volume

43

Issue

1

Start / End Page

24 / 27

Location

United States

Related Subject Headings

  • Prognosis
  • Oncology & Carcinogenesis
  • Male
  • Lymphohistiocytosis, Hemophagocytic
  • Infant
  • Humans
  • Histiocytosis, Langerhans-Cell
  • Antineoplastic Combined Chemotherapy Protocols
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hinson, A. R. P., Patel, N., & Kaplan, J. (2021). Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Report and Review of the Literature. J Pediatr Hematol Oncol, 43(1), 24–27. https://doi.org/10.1097/MPH.0000000000001652
Hinson, Ashley R. P., Niraj Patel, and Joel Kaplan. “Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Report and Review of the Literature.J Pediatr Hematol Oncol 43, no. 1 (January 2021): 24–27. https://doi.org/10.1097/MPH.0000000000001652.
Hinson ARP, Patel N, Kaplan J. Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Report and Review of the Literature. J Pediatr Hematol Oncol. 2021 Jan;43(1):24–7.
Hinson, Ashley R. P., et al. “Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Report and Review of the Literature.J Pediatr Hematol Oncol, vol. 43, no. 1, Jan. 2021, pp. 24–27. Pubmed, doi:10.1097/MPH.0000000000001652.
Hinson ARP, Patel N, Kaplan J. Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Report and Review of the Literature. J Pediatr Hematol Oncol. 2021 Jan;43(1):24–27.

Published In

J Pediatr Hematol Oncol

DOI

EISSN

1536-3678

Publication Date

January 2021

Volume

43

Issue

1

Start / End Page

24 / 27

Location

United States

Related Subject Headings

  • Prognosis
  • Oncology & Carcinogenesis
  • Male
  • Lymphohistiocytosis, Hemophagocytic
  • Infant
  • Humans
  • Histiocytosis, Langerhans-Cell
  • Antineoplastic Combined Chemotherapy Protocols
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology