Skip to main content
Journal cover image

Suicidal ideation and attempts in unipolar versus bipolar depression: analysis of 131,740 adolescent inpatients nationwide.

Publication ,  Journal Article
Patel, RS; Onyeaka, H; Youssef, NA
Published in: Psychiatry research
September 2020

Objective To evaluate the risk of suicidal ideation and suicidal attempt in adolescents with unipolar depression (UD) versus bipolar depression (BD). Method We included 131,740 adolescents (12-17y), with primary diagnoses of UD (92.6%) and BD (7.4%) from the nationwide inpatient sample. We calculated odds ratio (OR) for suicidal behaviors using logistic regression adjusted for demographic confounders and comorbidities. Results Suicidal ideation and suicidal attempt were seen in 14.5% and 38.6% respectively of total inpatients and both were seen in higher proportion of UD. Females have higher odds for suicidal attempt (OR 1.13, 95%CI 1.09-1.16) compared to males. After adjusting for confounders, UD had a marginally higher odds (OR 1.06, 95%CI 1.02-1.11) of suicidal attempt and 1.2 times higher odds (95%CI 1.11-1.26) of suicidal ideation compared to BD. Among adolescents with suicidal attempt, 93.2% had bipolar depression and 6.8% had unipolar depression.The majority of suicidal attempt in the inpatient setting was seen in females, with bipolar depression (74.6% vs. 67.3% in unipolar). Conclusion Our finding is clinically relevant and accentuates the need for early identification of BD, accurate differentiation of UD versus BD for targeted and adequate treatment to minimize suicidal behaviors, treat and manage them per treatment guidelines, and evolving research.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Psychiatry research

DOI

EISSN

1872-7123

ISSN

0165-1781

Publication Date

September 2020

Volume

291

Start / End Page

113231

Related Subject Headings

  • Suicide, Attempted
  • Suicidal Ideation
  • Risk Assessment
  • Psychiatry
  • Odds Ratio
  • Male
  • Logistic Models
  • Humans
  • Female
  • Depressive Disorder
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Patel, R. S., Onyeaka, H., & Youssef, N. A. (2020). Suicidal ideation and attempts in unipolar versus bipolar depression: analysis of 131,740 adolescent inpatients nationwide. Psychiatry Research, 291, 113231. https://doi.org/10.1016/j.psychres.2020.113231
Patel, Rikinkumar S., Henry Onyeaka, and Nagy A. Youssef. “Suicidal ideation and attempts in unipolar versus bipolar depression: analysis of 131,740 adolescent inpatients nationwide.Psychiatry Research 291 (September 2020): 113231. https://doi.org/10.1016/j.psychres.2020.113231.
Patel, Rikinkumar S., et al. “Suicidal ideation and attempts in unipolar versus bipolar depression: analysis of 131,740 adolescent inpatients nationwide.Psychiatry Research, vol. 291, Sept. 2020, p. 113231. Epmc, doi:10.1016/j.psychres.2020.113231.
Journal cover image

Published In

Psychiatry research

DOI

EISSN

1872-7123

ISSN

0165-1781

Publication Date

September 2020

Volume

291

Start / End Page

113231

Related Subject Headings

  • Suicide, Attempted
  • Suicidal Ideation
  • Risk Assessment
  • Psychiatry
  • Odds Ratio
  • Male
  • Logistic Models
  • Humans
  • Female
  • Depressive Disorder