Scholars@Duke publication: Piezo2 mediates visceral mechanosensation: A new therapeutic target for gut pain?

Piezo2 mediates visceral mechanosensation: A new therapeutic target for gut pain?

Publication , Journal Article

Xu, J; McGinnis, A; Ji, R-R

Published in: Neuron

February 15, 2023

Mechanical distension/stretch in the colon provokes visceral hypersensitivity and pain. In this issue of Neuron, Xie et al. report that mechanosensitive Piezo2 channels, expressed by TRPV1-lineage nociceptors, are involved in visceral mechanical nociception and hypersensitivity.

Duke Scholars

Author Ru-Rong Ji Anesthesiology

Published In

Neuron

DOI

10.1016/j.neuron.2023.01.011

EISSN

1097-4199

Publication Date

February 15, 2023

Volume

111

Issue

Start / End Page

450 / 452

Location

United States

Related Subject Headings

TRPV Cation Channels
Pain
Nociceptors
Neurons
Neurology & Neurosurgery
Ion Channels
Colon
5202 Biological psychology
3209 Neurosciences
1702 Cognitive Sciences

Citation

APA

Chicago

ICMJE

MLA

NLM

Xu, J., McGinnis, A., & Ji, R.-R. (2023). Piezo2 mediates visceral mechanosensation: A new therapeutic target for gut pain? Neuron, 111(4), 450–452. https://doi.org/10.1016/j.neuron.2023.01.011

Xu, Jing, Aidan McGinnis, and Ru-Rong Ji. “Piezo2 mediates visceral mechanosensation: A new therapeutic target for gut pain?” Neuron 111, no. 4 (February 15, 2023): 450–52. https://doi.org/10.1016/j.neuron.2023.01.011.

Xu J, McGinnis A, Ji R-R. Piezo2 mediates visceral mechanosensation: A new therapeutic target for gut pain? Neuron. 2023 Feb 15;111(4):450–2.

Xu, Jing, et al. “Piezo2 mediates visceral mechanosensation: A new therapeutic target for gut pain?” Neuron, vol. 111, no. 4, Feb. 2023, pp. 450–52. Pubmed, doi:10.1016/j.neuron.2023.01.011.

Xu J, McGinnis A, Ji R-R. Piezo2 mediates visceral mechanosensation: A new therapeutic target for gut pain? Neuron. 2023 Feb 15;111(4):450–452.