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Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke.

Publication ,  Journal Article
Blair, EM; Reale, BK; Zahuranec, DB; Forman, J; Langa, KM; Giordani, BJ; Plassman, BL; Welsh-Bohmer, KA; Wang, J; Kollman, CD; Levine, DA
Published in: J Stroke Cerebrovasc Dis
June 2023

GOALS: Evidence suggests that patients with mild cognitive impairment (MCI) receive fewer treatments for acute ischemic stroke and other cardiovascular diseases than patients with normal cognition. Little is known about how patient and care partner preferences for ischemic stroke treatment differ between the patient population with MCI and the population with normal cognition. This study aimed to understand how patient MCI diagnosis influences patient and care partner decision-making for acute ischemic stroke treatments. METHODS: Multi-center qualitative study using in-person semi-structured interviews with 20 MCI and normal cognition patient-care partner dyads using a standard guide. The present study reports results on patient and care partner preferences for a clinical vignette patient to receive three non-invasive treatments (intravenous tissue plasminogen activator, inpatient rehabilitation, and secondary preventive medications) and two invasive treatments (feeding tube and carotid endarterectomy) after acute ischemic stroke. We used qualitative content analysis to identify themes. FINDINGS: We identified three major themes: (1) Patients with MCI desired non-invasive treatments after stroke, similar to patients with normal cognition and for similar reasons; (2) Patients with MCI expressed different preferences than patients with normal cognition for two invasive treatments after stroke: carotid endarterectomy and feeding tube placement; and (3) Patients with MCI expressed more skepticism of the stroke treatment options and less decisiveness in decision-making than patients with normal cognition. CONCLUSIONS: These results suggest that patient MCI diagnosis may contribute to differences in patient and care partner preferences for invasive treatments after stroke, but not for non-invasive treatments.

Duke Scholars

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Published In

J Stroke Cerebrovasc Dis

DOI

EISSN

1532-8511

Publication Date

June 2023

Volume

32

Issue

6

Start / End Page

107068

Location

United States

Related Subject Headings

  • Tissue Plasminogen Activator
  • Stroke
  • Neurology & Neurosurgery
  • Ischemic Stroke
  • Humans
  • Cognitive Dysfunction
  • Caregivers
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
 

Citation

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Chicago
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MLA
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Blair, E. M., Reale, B. K., Zahuranec, D. B., Forman, J., Langa, K. M., Giordani, B. J., … Levine, D. A. (2023). Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke. J Stroke Cerebrovasc Dis, 32(6), 107068. https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107068
Blair, Emilie M., Bailey K. Reale, Darin B. Zahuranec, Jane Forman, Kenneth M. Langa, Bruno J. Giordani, Brenda L. Plassman, et al. “Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke.J Stroke Cerebrovasc Dis 32, no. 6 (June 2023): 107068. https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107068.
Blair EM, Reale BK, Zahuranec DB, Forman J, Langa KM, Giordani BJ, et al. Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke. J Stroke Cerebrovasc Dis. 2023 Jun;32(6):107068.
Blair, Emilie M., et al. “Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke.J Stroke Cerebrovasc Dis, vol. 32, no. 6, June 2023, p. 107068. Pubmed, doi:10.1016/j.jstrokecerebrovasdis.2023.107068.
Blair EM, Reale BK, Zahuranec DB, Forman J, Langa KM, Giordani BJ, Plassman BL, Welsh-Bohmer KA, Wang J, Kollman CD, Levine DA. Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke. J Stroke Cerebrovasc Dis. 2023 Jun;32(6):107068.
Journal cover image

Published In

J Stroke Cerebrovasc Dis

DOI

EISSN

1532-8511

Publication Date

June 2023

Volume

32

Issue

6

Start / End Page

107068

Location

United States

Related Subject Headings

  • Tissue Plasminogen Activator
  • Stroke
  • Neurology & Neurosurgery
  • Ischemic Stroke
  • Humans
  • Cognitive Dysfunction
  • Caregivers
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences