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Periprocedural Complications With Balloon Pulmonary Angioplasty: Analysis of Global Studies.

Publication ,  Journal Article
Jain, N; Sheikh, MA; Bajaj, D; Townsend, W; Krasuski, R; Secemsky, E; Chatterjee, S; Moles, V; Agarwal, PP; Haft, J; Visovatti, SH ...
Published in: JACC Cardiovasc Interv
April 24, 2023

BACKGROUND: Balloon pulmonary angioplasty (BPA) was introduced as a treatment modality for patients with inoperable, medically refractory chronic thromboembolic pulmonary hypertension decades ago; however, reports of high rates of pulmonary vascular injury have led to considerable refinement in procedural technique. OBJECTIVES: The authors sought to better understand the evolution of BPA procedure-related complications over time. METHODS: The authors conducted a systematic review of original articles published by pulmonary hypertension centers globally and performed a pooled cohort analysis of procedure-related outcomes with BPA. RESULTS: This systematic review identified 26 published articles from 18 countries worldwide from 2013 to 2022. A total of 1,714 patients underwent 7,561 total BPA procedures with an average follow up of 7.3 months. From the first period (2013-2017) to the second period (2018-2022), the cumulative incidence of hemoptysis/vascular injury decreased from 14.1% (474/3,351) to 7.7% (233/3,029) (P < 0.01); lung injury/reperfusion edema decreased from 11.3% (377/3,351) to 1.4% (57/3,943) (P < 0.01); invasive mechanical ventilation decreased from 0.7% (23/3,195) to 0.1% (4/3,062) (P < 0.01); and mortality decreased from 2.0% (13/636) to 0.8% (8/1,071) (P < 0.01). CONCLUSIONS: Procedure-related complications with BPA, including hemoptysis/vascular injury, lung injury/reperfusion edema, mechanical ventilation, and death, were less common in the second period (2018-2022), compared with first period (2013-2017), likely from refinement in patient and lesion selection and procedural technique over time.

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Published In

JACC Cardiovasc Interv

DOI

EISSN

1876-7605

Publication Date

April 24, 2023

Volume

16

Issue

8

Start / End Page

976 / 983

Location

United States

Related Subject Headings

  • Vascular System Injuries
  • Treatment Outcome
  • Pulmonary Embolism
  • Pulmonary Edema
  • Pulmonary Artery
  • Lung Injury
  • Hypertension, Pulmonary
  • Humans
  • Hemoptysis
  • Edema
 

Citation

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Jain, N., Sheikh, M. A., Bajaj, D., Townsend, W., Krasuski, R., Secemsky, E., … Aggarwal, V. (2023). Periprocedural Complications With Balloon Pulmonary Angioplasty: Analysis of Global Studies. JACC Cardiovasc Interv, 16(8), 976–983. https://doi.org/10.1016/j.jcin.2023.01.361
Jain, Nishant, Muhammad A. Sheikh, Divyansh Bajaj, Whitney Townsend, Richard Krasuski, Eric Secemsky, Saurav Chatterjee, et al. “Periprocedural Complications With Balloon Pulmonary Angioplasty: Analysis of Global Studies.JACC Cardiovasc Interv 16, no. 8 (April 24, 2023): 976–83. https://doi.org/10.1016/j.jcin.2023.01.361.
Jain N, Sheikh MA, Bajaj D, Townsend W, Krasuski R, Secemsky E, et al. Periprocedural Complications With Balloon Pulmonary Angioplasty: Analysis of Global Studies. JACC Cardiovasc Interv. 2023 Apr 24;16(8):976–83.
Jain, Nishant, et al. “Periprocedural Complications With Balloon Pulmonary Angioplasty: Analysis of Global Studies.JACC Cardiovasc Interv, vol. 16, no. 8, Apr. 2023, pp. 976–83. Pubmed, doi:10.1016/j.jcin.2023.01.361.
Jain N, Sheikh MA, Bajaj D, Townsend W, Krasuski R, Secemsky E, Chatterjee S, Moles V, Agarwal PP, Haft J, Visovatti SH, Cascino TM, Rosenfield K, Nallamothu BK, Mclaughlin VV, Aggarwal V. Periprocedural Complications With Balloon Pulmonary Angioplasty: Analysis of Global Studies. JACC Cardiovasc Interv. 2023 Apr 24;16(8):976–983.
Journal cover image

Published In

JACC Cardiovasc Interv

DOI

EISSN

1876-7605

Publication Date

April 24, 2023

Volume

16

Issue

8

Start / End Page

976 / 983

Location

United States

Related Subject Headings

  • Vascular System Injuries
  • Treatment Outcome
  • Pulmonary Embolism
  • Pulmonary Edema
  • Pulmonary Artery
  • Lung Injury
  • Hypertension, Pulmonary
  • Humans
  • Hemoptysis
  • Edema