Figure S2 from Deconstructing olfactory epithelium developmental pathways in olfactory neuroblastoma

<p>RNA expression signatures of ONB from Classe et al., 2018 based on markers traditionally associated with sinonasal undifferentiated carcinoma (A), small cell neuroendocrine carcinoma (B), and olfactory neuroblastoma (C), divided by control OE, low grade ONB, high grade ONB, and IDH2 mutant ONB. A) Expression of keratins is not significantly increased in IDH2 mutant ONB versus IDH2 wild type tumors. B) Small cell neuroendocrine carcinoma (SNEC) marker genes are not highly expressed ONB from Classe et al. dataset. C) Expression of canonical neuroendocrine markers is negatively associated with ONB grade, and is not significantly different between high grade IDH2 and high grade IDH2 mutant ONB.</p>

Duke Scholars

Author David W Jang Rhinology and Skull Base Surgery

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