Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections.
Publication
, Journal Article
Sweeney, DA; Tuyishimire, B; Ahuja, N; Beigel, JH; Beresnev, T; Cantos, VD; Castro, JG; Cohen, SH; Cross, K; Dodd, LE; Erdmann, N; Fung, M ...
Published in: Open Forum Infect Dis
May 2023
We performed a secondary analysis of the National Institutes of Health-sponsored Adaptive COVID-19 Treatment Trial (ACTT-2) randomized controlled trial and found that baricitinib was associated with a 50% reduction in secondary infections after controlling for baseline and postrandomization patient characteristics. This finding provides a novel mechanism of benefit for baricitinib and supports the safety profile of this immunomodulator for the treatment of coronavirus disease 2019.
Duke Scholars
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Published In
Open Forum Infect Dis
DOI
ISSN
2328-8957
Publication Date
May 2023
Volume
10
Issue
5
Start / End Page
ofad205
Location
United States
Related Subject Headings
- 3207 Medical microbiology
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Sweeney, D. A., Tuyishimire, B., Ahuja, N., Beigel, J. H., Beresnev, T., Cantos, V. D., … Kalil, A. C. (2023). Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections. Open Forum Infect Dis, 10(5), ofad205. https://doi.org/10.1093/ofid/ofad205
Sweeney, Daniel A., Bonifride Tuyishimire, Neera Ahuja, John H. Beigel, Tatiana Beresnev, Valeria D. Cantos, Jose G. Castro, et al. “Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections.” Open Forum Infect Dis 10, no. 5 (May 2023): ofad205. https://doi.org/10.1093/ofid/ofad205.
Sweeney DA, Tuyishimire B, Ahuja N, Beigel JH, Beresnev T, Cantos VD, et al. Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections. Open Forum Infect Dis. 2023 May;10(5):ofad205.
Sweeney, Daniel A., et al. “Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections.” Open Forum Infect Dis, vol. 10, no. 5, May 2023, p. ofad205. Pubmed, doi:10.1093/ofid/ofad205.
Sweeney DA, Tuyishimire B, Ahuja N, Beigel JH, Beresnev T, Cantos VD, Castro JG, Cohen SH, Cross K, Dodd LE, Erdmann N, Fung M, Ghazaryan V, George SL, Grimes KA, Hynes NA, Julian KG, Kandiah S, Kim HJ, Levine CB, Lindholm DA, Lye DC, Maves RC, Oh M-D, Paules C, Rapaka RR, Short WR, Tomashek KM, Wolfe CR, Kalil AC. Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections. Open Forum Infect Dis. 2023 May;10(5):ofad205.
Published In
Open Forum Infect Dis
DOI
ISSN
2328-8957
Publication Date
May 2023
Volume
10
Issue
5
Start / End Page
ofad205
Location
United States
Related Subject Headings
- 3207 Medical microbiology
- 3202 Clinical sciences