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Clinical utility of ultrasound and MRI in rheumatoid arthritis: An expert review.

Publication ,  Journal Article
Kellner, DA; Morris, NT; Lee, SM; Baker, JF; Chu, P; Ranganath, VK; Kaeley, GS; Yang, HH
Published in: Best Pract Res Clin Rheumatol
September 2025

Musculoskeletal ultrasound (MSUS) and magnetic resonance imaging (MRI) are advanced imaging techniques that are increasingly important in the diagnosis and management of rheumatoid arthritis (RA) and have significantly enhanced the rheumatologist's ability to assess RA disease activity and progression. This review serves as a five-year update to our previous publication on the contemporary role of imaging in RA, emphasizing the continued importance of MSUS and MRI in clinical practice and their expanding utility. The review examines the role of MSUS in diagnosing RA, differentiating RA from mimickers, scoring systems and quality control measures, novel longitudinal approaches to disease monitoring, and patient populations that may benefit most from MSUS. It also examines the role of MRI in diagnosing pre-clinical and early RA, disease activity monitoring, research and clinical trials, and development of alternative scoring approaches utilizing artificial intelligence. Finally, the role of MRI in RA diagnosis and management is summarized, and selected practice points offer key tips for integrating MSUS and MRI into clinical practice.

Duke Scholars

Published In

Best Pract Res Clin Rheumatol

DOI

EISSN

1532-1770

Publication Date

September 2025

Volume

39

Issue

3

Start / End Page

102072

Location

Netherlands

Related Subject Headings

  • Ultrasonography
  • Severity of Illness Index
  • Magnetic Resonance Imaging
  • Humans
  • Disease Progression
  • Arthritis, Rheumatoid
  • Arthritis & Rheumatology
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kellner, D. A., Morris, N. T., Lee, S. M., Baker, J. F., Chu, P., Ranganath, V. K., … Yang, H. H. (2025). Clinical utility of ultrasound and MRI in rheumatoid arthritis: An expert review. Best Pract Res Clin Rheumatol, 39(3), 102072. https://doi.org/10.1016/j.berh.2025.102072
Kellner, David A., Nicolette T. Morris, Stephanie M. Lee, Joshua F. Baker, Philip Chu, Veena K. Ranganath, Gurjit S. Kaeley, and Howard H. Yang. “Clinical utility of ultrasound and MRI in rheumatoid arthritis: An expert review.Best Pract Res Clin Rheumatol 39, no. 3 (September 2025): 102072. https://doi.org/10.1016/j.berh.2025.102072.
Kellner DA, Morris NT, Lee SM, Baker JF, Chu P, Ranganath VK, et al. Clinical utility of ultrasound and MRI in rheumatoid arthritis: An expert review. Best Pract Res Clin Rheumatol. 2025 Sep;39(3):102072.
Kellner, David A., et al. “Clinical utility of ultrasound and MRI in rheumatoid arthritis: An expert review.Best Pract Res Clin Rheumatol, vol. 39, no. 3, Sept. 2025, p. 102072. Pubmed, doi:10.1016/j.berh.2025.102072.
Kellner DA, Morris NT, Lee SM, Baker JF, Chu P, Ranganath VK, Kaeley GS, Yang HH. Clinical utility of ultrasound and MRI in rheumatoid arthritis: An expert review. Best Pract Res Clin Rheumatol. 2025 Sep;39(3):102072.
Journal cover image

Published In

Best Pract Res Clin Rheumatol

DOI

EISSN

1532-1770

Publication Date

September 2025

Volume

39

Issue

3

Start / End Page

102072

Location

Netherlands

Related Subject Headings

  • Ultrasonography
  • Severity of Illness Index
  • Magnetic Resonance Imaging
  • Humans
  • Disease Progression
  • Arthritis, Rheumatoid
  • Arthritis & Rheumatology
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
  • 1103 Clinical Sciences